NCT03122197 2026-04-16
Study of Letrozole in Recurrent Gliomas
University of Cincinnati
Phase EARLY_PHASE1 Recruiting
Clinical Trials
46 trialsNCT04655404 2026-03-18
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
NCT06333899 2026-03-12
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
NCT07268053 2026-03-06
A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT07284069 2026-03-04
SENIPERA
University of Aarhus
Phase EARLY_PHASE1 Recruiting
NCT05636540 2026-02-27
In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma
Abramson Cancer Center at Penn Medicine
Phase EARLY_PHASE1 Recruiting
NCT05804227 2026-02-27
Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Recruiting
NCT06942039 2026-02-27
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
C17 Council
Phase EARLY_PHASE1 Recruiting
NCT06636162 2026-02-23
Window of Opportunity Study of DSP-0390 in Gliomas
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT07076472 2026-02-23
Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT07050836 2026-02-04
Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation
University of Colorado, Denver
Phase EARLY_PHASE1 Recruiting
NCT07025226 2026-01-26
Senolytics
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT05851378 2026-01-12
Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma
University of California, San Francisco
Phase EARLY_PHASE1 Recruiting
NCT06829173 2026-01-02
Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas
NYU Langone Health
Phase EARLY_PHASE1 Recruiting
NCT06645808 2025-12-29
VARTUTRACE
Var2 Pharmaceuticals
Phase EARLY_PHASE1 Recruiting
NCT05423210 2025-12-22
Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme
Stony Brook University
Phase EARLY_PHASE1 Recruiting
NCT04943913 2025-12-11
Study of GC101 TIL in Brain Glioma (Soochow2)
Shanghai Juncell Therapeutics
Phase EARLY_PHASE1 Recruiting
NCT05632562 2025-12-11
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
University of Alabama at Birmingham
Phase EARLY_PHASE1 Recruiting
NCT07077616 2025-12-08
TAMAVAQTM
Biogenea Pharmaceuticals Ltd.
Phase EARLY_PHASE1 Recruiting
NCT05553041 2025-12-04
18F-Fluciclovine PET-MRI in High-grade Glioma
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT05555550 2025-12-04
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT06613841 2025-11-28
GBM
Abramson Cancer Center at Penn Medicine
Phase EARLY_PHASE1 Recruiting
NCT06072586 2025-11-20
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT06831526 2025-11-12
Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT05717153 2025-11-04
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT06328686 2025-09-17
Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases
Emory University
Phase EARLY_PHASE1 Recruiting
NCT06552260 2025-09-11
A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma
Dana-Farber Cancer Institute
Phase EARLY_PHASE1 Recruiting
NCT07067346 2025-07-29
Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma
Sichuan University
Phase EARLY_PHASE1 Recruiting
NCT04135807 2025-07-23
Implantable Microdevice In Primary Brain Tumors
Brigham and Women's Hospital
Phase EARLY_PHASE1 Recruiting
NCT07067905 2025-07-16
Clinical Evaluation of [68Ga]Ga-XT771 PET for Diagnosis in Patients With Glioblastoma and Clear Cell Renal Cell Carcinoma
Chinese PLA General Hospital
Phase EARLY_PHASE1 Recruiting
NCT06632860 2025-07-09
A Dual-targeting Tracer TATE-RGD for the Diagnosis of SSTR- and RGD- Positive Tumors
Peking Union Medical College Hospital
Phase EARLY_PHASE1 Recruiting
NCT06883747 2025-06-19
Clinical Trial of BMS-986504 in Recurrent GBM Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT05380349 2025-05-16
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Swedish Medical Center
Phase EARLY_PHASE1 Recruiting
NCT06959979 2025-05-07
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase EARLY_PHASE1 Recruiting
NCT05432518 2025-04-25
Pilot Trial for Treatment of Recurrent Glioblastoma
AHS Cancer Control Alberta
Phase EARLY_PHASE1 Recruiting
NCT04559685 2025-03-14
Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT05773326 2025-02-27
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT06828341 2025-02-14
A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression
Jinling Hospital, China
Phase EARLY_PHASE1 Recruiting
NCT06757153 2025-01-03
Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients
Zhongnan Hospital
Phase EARLY_PHASE1 Recruiting
NCT06684639 2024-12-20
A Study on the Efficacy of GD2-CAR T Cells in the Treatment of Neuroblastoma
The General Hospital of Western Theater Command
Phase EARLY_PHASE1 Recruiting
NCT05996432 2024-09-23
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Recruiting
NCT05549024 2024-07-05
68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients
Peking Union Medical College Hospital
Phase EARLY_PHASE1 Recruiting
NCT06412952 2024-05-14
68Ga-NOTA-RM26 PET/CT in Glioma Patients
Peking Union Medical College Hospital
Phase EARLY_PHASE1 Recruiting
NCT05043701 2024-04-03
ISM-GBM
Oslo University Hospital
Phase EARLY_PHASE1 Recruiting
NCT05069220 2024-03-01
18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor
Peking Union Medical College Hospital
Phase EARLY_PHASE1 Recruiting
NCT05961111 2023-07-27
A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors
Shanghai Yunying Medical Technology
Phase EARLY_PHASE1 Recruiting