Clinical Trials

24 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioblastoma, Glioma

NCT07558473 2026-05-22

Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors

300 enrolled

Brain Neoplasms, Neoplasms

NCT07604285 2026-05-22

NOVA-GBM

36 enrolled

Glioblastoma

NCT07590726 2026-05-19

PIRe

160 enrolled

Brain Injuries, Traumatic, Margins of Excision, Caregiver Burden, Brain Injuries, Brain Neoplasms, Communication, Glioblastoma, Neoplasms, Neurologic Manifestations, Stroke

NCT07392957 2026-05-14

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

54 enrolled

Glioblastoma

NCT07422363 2026-05-13

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT07579208 2026-05-12

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

36 enrolled

Glioblastoma

NCT06804655 2026-05-06

EViDENCE-BT

40 enrolled

Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Neurologic Manifestations

NCT07569263 2026-05-06

IMPACT MET

12 enrolled

Brain Neoplasms

NCT07570485 2026-05-06

APATC

90 enrolled

Brain Neoplasms

NCT07271966 2026-05-05

BALANCE

50 enrolled

Brain Neoplasms

NCT07567469 2026-05-05

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma

120 enrolled

Ependymoma, Glioma, Neoplasms, Recurrence

NCT07375992 2026-05-04

MELODY

35 enrolled

Phase 3 Not yet recruiting

Glioblastoma

NCT07452458 2026-05-04

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

398 enrolled

Glioblastoma

NCT07539753 2026-04-30

Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases

46 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT07558395 2026-04-30

REVIIH-BT

120 enrolled

Brain Neoplasms, Hemianopsia

NCT04903795 2026-04-27

BRiTE

18 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Glioblastoma

NCT05676489 2026-04-27

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

28 enrolled

Glioma

NCT07551414 2026-04-24

Zorifertinib Plus Intra-Ommaya CSF Chemotherapy for Leptomeningeal Progression in NSCLC After Third-Generation EGFR-TKI

38 enrolled

CNSThoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT07402343 2026-04-23

T-BRAIN

Phase 4 Not yet recruiting

35 enrolled

CNSThoracic

Brain Neoplasms, Small Cell Lung Carcinoma

NCT07546669 2026-04-23

STARGATE

230 enrolled

Glioblastoma

NCT07541781 2026-04-21

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

45 enrolled

Phase 2/3 Not yet recruiting

Glioblastoma, Glioma

NCT07542288 2026-04-21

Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases:

400 enrolled

Brain Neoplasms

NCT07537400 2026-04-17

Patients Between the Ages of 12 Months to 21 Years With Newly-Diagnosed High-Risk Neuroblastoma Will Receive Children's Oncology Group (COG) Type Recommended Therapy With the Addition of Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Induction Cycles 1-5

10 enrolled

Neuroblastoma

NCT07533942 2026-04-16

A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma

Meningioma

NCT07437963 2026-04-15

Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse

76 enrolled

Neuroblastoma, Ganglioneuroblastoma

NCT07527169 2026-04-14

A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory Neuroblastoma

16 enrolled

Esthesioneuroblastoma, Olfactory

NCT07527884 2026-04-14

The Effect of Radiotherapy After Separation Surgery for Spinal Metastases

130 enrolled

Spinal Cord Neoplasms

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

33 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT07505979 2026-04-13

SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases

90 enrolled

Brain Neoplasms

NCT07521657 2026-04-13

NF118

55 enrolled

Glioblastoma, Glioma, Neurofibromatosis 1

NCT07520370 2026-04-09

Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor

1,370 enrolled

Brain Neoplasms, Stroke

NCT07206849 2026-04-08

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

79 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma

NCT07248228 2026-04-08

Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)

90 enrolled

Brain Neoplasms

NCT07516353 2026-04-08

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

CNSLymphoidOther hematologic neoplasmSarcoma

143 enrolled

Medulloblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07518654 2026-04-08

ThINKK-01

CNSLymphoidOther hematologic neoplasm

12 enrolled

Paroxysmal nonkinesigenic dyskinesia, Leukemia, Neoplasm Metastasis, Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07515924 2026-04-07

Oral Gallium Maltolate for Recurrent Glioblastoma

Phase EARLY_PHASE1 Not yet recruiting

8 enrolled

Glioblastoma

NCT07449481 2026-04-01

A Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors

56 enrolled

Brain Neoplasms

NCT07431216 2026-03-30

A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression

68 enrolled

Glioblastoma

NCT07496073 2026-03-27

A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN）

Brain Neoplasms, Neoplasms, Neurologic Manifestations

NCT07492680 2026-03-25

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

CNSDermatologicGastrointestinal

260 enrolled

Brain Neoplasms, Melanoma, Pancreatic Neoplasms

NCT07492836 2026-03-25

HipoGBM

10 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Glioblastoma

NCT07493447 2026-03-25

Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures

CNSEndocrine

Brain Neoplasms, Glioblastoma, Meningioma, Neoplasms, Neuroma, Acoustic, Pituitary Neoplasms

NCT07089758 2026-03-23

A Study for Cerebral Open Flow Microperfusion

6 enrolled

Glioblastoma, Glioma

NCT07488780 2026-03-23

Language Network Prehab Via fMRI Neurofeedback

4 enrolled

Glioma

NCT06858501 2026-03-19

Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma

84 enrolled