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Phase

Phase 1/2 1

Status

Withdrawn 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1Classical hematology 1

Conditions

Myeloproliferative Disorders 1Anemia, Refractory, with Excess of Blasts 1

Interventions

Peripheral Blood Stem Cell Transplantation 4fludarabine phosphate 2Whole-Body Irradiation 2Methotrexate 2Cyclosporine 2Cyclophosphamide 2Busulfan 2siltuximab 1pegylated granulocyte colony-stimulating factor 1magrolimab 1hetrombopag 1fludarabine 1ferric gluconate 1decitabine and cedazuridine drug combination 1ceftolozane, tazobactam drug combination 1avatrombopag 1Transplantation 1Tacrolimus 1Radiotherapy 1Pluvicto 1Pentostatin 1Mycophenolic Acid 1Micafungin 1Meropenem 1Iron-Dextran Complex 1Iron 1In Situ Hybridization, Fluorescence 1Immunoenzyme Techniques 1Holistic Health 1Genotype 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × ASTX029 × Classical hematology × Clear all
NCT06284460 2026-02-13

Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms

M.D. Anderson Cancer Center

Phase 1/2 Withdrawn
Classical hematologyMyeloid

Anemia, Refractory, with Excess of Blasts, Myeloproliferative Disorders

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