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Phase

Phase 2 5Phase 1 4Phase 2/3 2Phase 1/2 2Phase 3 1

Status

Recruiting 1Completed 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 9Myeloid 4Lymphoid 2Classical hematology 2

Conditions

Myelodysplastic Syndromes 2Leukemia, Myeloid, Acute 2Leukemia 2Anemia, Refractory, with Excess of Blasts 2Leukemia, Myelomonocytic, Chronic 1Leukemia, Myelomonocytic, Acute 1Leukemia, Monocytic, Acute 1Leukemia, Megakaryoblastic, Acute 1Leukemia, Erythroblastic, Acute 1Leukemia, Eosinophilic, Acute 1Leukemia, Basophilic, Acute 1Hematologic Diseases 1Congenital Abnormalities 1

Interventions

fludarabine phosphate 3Filgrastim 3Cyclophosphamide 3eltrombopag 2Radiotherapy 2Methylprednisolone 2Melphalan 2Cytarabine 2Busulfan 2Azacitidine 2Antilymphocyte Serum 2venetoclax 1tipifarnib 1cedazuridine 1Whole-Body Irradiation 1Thiotepa 1Tacrolimus 1Rivaroxaban 1Methotrexate 1Immunologic Techniques 1Granulocyte Colony-Stimulating Factor 1Gene Expression Profiling 1Gemtuzumab 1Etoposide 1Daunorubicin 1Darbepoetin alfa 1DNA Methylation 1Cytogenetic Analysis 1Cyclosporine 1Clofarabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Azacitidine × Classical hematology × Clear all
NCT04256317 2026-04-30

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Taiho Oncology, Inc.

Phase 2/3 Recruiting
316 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT00454480 2013-08-26

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

National Cancer Institute (NCI)

Phase 2/3 Completed
2,000 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

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