Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 51Gastrointestinal 46Genitourinary 41Gynecologic 27Other 24Head & Neck 21Thoracic 20CNS 15Other hematologic neoplasm 11Lymphoid 11Dermatologic 8Tumor-Agnostic 7Sarcoma 6Other solid neoplasm 5Plasma cell 3Endocrine 3NET 2Classical hematology 2Other neoplasm 1

Conditions

Weight Loss 1Thrombocytopenia 1Splenomegaly 1Preleukemia 1Multiple Myeloma 1Lymphocytosis 1Lymphadenopathy 1Leukemia, Lymphocytic, Chronic, B-Cell 1Fever 1Fatigue 1Cytopenia 1Anemia, Refractory, with Excess of Blasts 1Anemia 1

Interventions

Cyclophosphamide 94fludarabine phosphate 87Busulfan 64Cyclosporine 57Epoetin Alfa 55Peripheral Blood Stem Cell Transplantation 54Mycophenolic Acid 54Whole-Body Irradiation 53fludarabine 45Antilymphocyte Serum 43Filgrastim 41Cytarabine 41Melphalan 40Tacrolimus 39Darbepoetin alfa 39Methotrexate 34Radiotherapy 33Cord Blood Stem Cell Transplantation 28Granulocyte Colony-Stimulating Factor 23apixaban 22Methylprednisolone 22Rivaroxaban 21Etoposide 21Thiotepa 17Dalteparin 17eltrombopag 16ferric carboxymaltose 14epoetin beta 14Daunorubicin 14Azacitidine 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Metformin × Classical hematology × Clear all
NCT04741945 2024-11-22

Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS

Rigshospitalet, Denmark

Phase 2 Recruiting
40 enrolled
Classical hematologyOther hematologic neoplasm

Cytopenia, Anemia, Refractory, with Excess of Blasts, Preleukemia

NCT02948283 2021-02-12

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

City of Hope Medical Center

Phase 1 Completed
3 enrolled
Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

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