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Phase

Phase 1 16Phase 2 2Phase EARLY_PHASE1 1Phase 3 1Phase 1/2 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 174Sarcoma 68Head & Neck 6Lymphoid 5Gastrointestinal 4Endocrine 4Thoracic 3Other solid neoplasm 3Gynecologic 2Genitourinary 2Dermatologic 2Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Melanoma 862Lymphoma, T-Cell, Cutaneous 143Uveal Melanoma 97Skin Neoplasms 96Mycosis Fungoides 95Sezary Syndrome 81Carcinoma, Basal Cell 76Neoplasm Metastasis 68Lymphoma 64Lymphoma, Non-Hodgkin 63Keratosis, Actinic 61Neoplasms 57Leukemia, Lymphocytic, Chronic, B-Cell 57Carcinoma, Renal Cell 55Carcinoma, Non-Small-Cell Lung 54Lymphoma, B-Cell, Marginal Zone 53Precursor Cell Lymphoblastic Leukemia-Lymphoma 52Lymphoma, Mantle-Cell 52Lymphoma, Large B-Cell, Diffuse 52Lymphoma, Follicular 52Hodgkin Disease 52Lymphoma, Large-Cell, Immunoblastic 50Carcinoma, Merkel Cell 50Burkitt Lymphoma 49Brain Neoplasms 46Multiple Myeloma 44Lymphoma, Large-Cell, Anaplastic 41Recurrence 40Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 40Breast Neoplasms 40

Interventions

tovorafenib 1Immunologic Techniques 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Astrocytoma × Dermatologic × Clear all
NCT04985604 2025-10-02

Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors

Day One Biopharmaceuticals, Inc.

Phase 2 Terminated
23 enrolled 15 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckThoracic

Thyroid Cancer, Papillary, Astrocytoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Memorial Sloan Kettering Cancer Center

Phase 2 Completed
78 enrolled 11 charts
CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

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