Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 8Thoracic 1Sarcoma 1Dermatologic 1Breast 1

Conditions

Melanoma 783Carcinoma, Non-Small-Cell Lung 170Skin Neoplasms 154Neoplasms 106Neoplasm Metastasis 100Colorectal Neoplasms 97Carcinoma, Renal Cell 95Uveal Melanoma 92Breast Neoplasms 88Squamous Cell Carcinoma of Head and Neck 85Carcinoma, Basal Cell 83Lung Neoplasms 81Ovarian Neoplasms 79Sarcoma 67Lymphoma, T-Cell, Cutaneous 66Carcinoma, Merkel Cell 66Stomach Neoplasms 58Pancreatic Neoplasms 58Head and Neck Neoplasms 55Carcinoma, Hepatocellular 53Uterine Cervical Neoplasms 52Urinary Bladder Neoplasms 50Esophageal Neoplasms 44Prostatic Neoplasms 43Triple Negative Breast Neoplasms 42Endometrial Neoplasms 41Carcinoma, Squamous Cell 39Brain Neoplasms 39Carcinoma, Transitional Cell 37Lymphoma 35

Interventions

binimetinib 1PF-07284890 1Midazolam 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Brain Diseases × Dermatologic × 1 year × Clear all
NCT04543188 2025-10-23

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Pfizer

Phase 1 Terminated
65 enrolled 52 charts
CNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Central Nervous System Neoplasms

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