Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 5Thoracic 1Sarcoma 1Dermatologic 1

Conditions

Melanoma 488Lymphoma, T-Cell, Cutaneous 92Carcinoma, Non-Small-Cell Lung 89Mycosis Fungoides 72Neoplasm Metastasis 71Skin Neoplasms 62Neoplasms 61Sezary Syndrome 60Carcinoma, Renal Cell 60Lymphoma, Non-Hodgkin 53Lymphoma, Large B-Cell, Diffuse 53Lymphoma 53Breast Neoplasms 52Leukemia, Lymphocytic, Chronic, B-Cell 50Lymphoma, Follicular 47Lymphoma, Mantle-Cell 46Lymphoma, B-Cell, Marginal Zone 46Squamous Cell Carcinoma of Head and Neck 45Precursor Cell Lymphoblastic Leukemia-Lymphoma 44Hodgkin Disease 44Colorectal Neoplasms 43Burkitt Lymphoma 43Lymphoma, Large-Cell, Immunoblastic 41Ovarian Neoplasms 38Multiple Myeloma 35Uveal Melanoma 34Leukemia, Hairy Cell 33Lymphoma, Large-Cell, Anaplastic 32Sarcoma 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 31

Interventions

binimetinib 1PF-07284890 1Midazolam 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Brain Diseases × Dermatologic × Clear all
NCT04543188 2025-10-23

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Pfizer

Phase 1 Terminated
65 enrolled 52 charts
CNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Central Nervous System Neoplasms

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