Clinical Trials

Carcinoma, Basal Cell, Melanoma, Skin Neoplasms

NCT03610022 2026-05-19

OPTIVISMO-1

Phase 4 Completed

27 enrolled

Carcinoma, Basal Cell

NCT07285044 2026-05-18

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT02834013 2026-05-13

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

818 enrolled

Nasopharyngeal Carcinoma, Bile Duct Neoplasms, Carcinoma, Basal Cell, Adenocarcinoma, Bronchiolo-Alveolar, Adenocarcinoma, Mucinous, Carcinoma, Transitional Cell, Carcinosarcoma, Chordoma, Carcinoma, Adenoid Cystic, Fibroma, Gallbladder Neoplasms, Hemangiosarcoma, Mouth Neoplasms, Paget Disease, Extramammary, Paraganglioma, Paranasal Sinus Neoplasms, Parathyroid Neoplasms, Pheochromocytoma, Pseudomyxoma Peritonei, Somatostatinoma, Thyroid Neoplasms, Vulvar Neoplasms, Desmoid Tumors, Seminoma, Carcinoma, Acinar Cell, Adrenocortical Carcinoma, Carcinoma, Endometrioid, Cholangiocarcinoma, Cystadenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Carcinoma, Giant Cell, Neurofibrosarcoma, Gestational Trophoblastic Disease, Rare Diseases, Gastrointestinal Stromal Tumors, Perivascular Epithelioid Cell Neoplasms

NCT02978625 2026-05-13

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

68 enrolled

DermatologicLymphoid

Microcystic adnexal carcinoma, Adenocarcinoma, Papillary, Carcinoma, Basal Cell, Carcinoma, Basosquamous, Mycosis Fungoides, Paget Disease, Extramammary, Sezary Syndrome, Carcinoma, Merkel Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Carcinoma, Signet Ring Cell, Muir-Torre Syndrome, Eccrine Porocarcinoma

NCT05896839 2026-05-13

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Phase 1/2 Recruiting

16 enrolled

Carcinoma, Basal Cell, Melanoma, Carcinoma, Merkel Cell

NCT00833417 2026-05-11

A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell Carcinoma

104 enrolled 13 charts

Carcinoma, Basal Cell, Neoplasms, Basal Cell

NCT07455331 2026-05-11

LANCE

Carcinoma, Basal Cell, Skin Neoplasms

NCT00959647 2026-05-08

A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study

DermatologicGastrointestinalGynecologic

19 enrolled 10 charts

Carcinoma, Basal Cell, Ovarian Neoplasms, Colorectal Neoplasms

NCT05212246 2026-05-08

B3C

Phase 3 Not yet recruiting

1,630 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Patient Compliance, Keratosis, Actinic

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

50 enrolled

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT06608238 2026-05-04

Phase 2 Study Evaluating the Safety and Efficacy of Microneedle-mediated Delivery of Doxorubicin (D-MNA) in Patients With Nodular Basal Cell Carcinoma.

90 enrolled

Phase 1 Active not recruiting

Carcinoma, Basal Cell

NCT03816332 2026-04-30

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

12 enrolled 13 charts

Carcinoma, Basal Cell, Melanoma, Carcinoma, Merkel Cell

NCT03521830 2026-04-29

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

57 enrolled

Carcinoma, Basal Cell

NCT06919809 2026-04-24

Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery

16 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT02667574 2026-04-22

VISMONEO

55 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Basal Cell

NCT04349436 2026-04-22

ARTACUS

69 enrolled

Carcinoma, Carcinoma, Basal Cell, Neoplasms, Skin Neoplasms, Carcinoma, Merkel Cell

NCT05294120 2026-04-20

A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma

38 enrolled

Carcinoma, Basal Cell

NCT03646188 2026-04-16

Dose Escalation Trial to Evaluate Dose Limiting Toxicity/Maximum Tolerated Dose of Microneedle Arrays Containing Doxorubicin (D-MNA) in Basal Cell Carcinoma (BCC)

Phase 1 Terminated

13 enrolled 12 charts

Carcinoma, Basal Cell

NCT06539468 2026-04-14

Active Surveillance for the Treatment of Low-Risk Basal Cell Carcinoma in Elderly Patients

Phase NA Recruiting

200 enrolled

Carcinoma, Basal Cell

NCT03737734 2026-04-06

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05814900 2026-04-02

Investigation of Mohs Surgical Margins Using Two Photon Microscopy

135 enrolled 8 charts

Phase EARLY_PHASE1 Not yet recruiting

Carcinoma, Basal Cell

NCT07286318 2026-04-02

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

20 enrolled

Carcinoma, Basal Cell, Skin Neoplasms, Keratosis, Actinic

NCT05724875 2026-03-27

LANCE

Phase EARLY_PHASE1 Completed

Carcinoma, Basal Cell

NCT04480645 2026-03-24

CivaDerm(TM) Surface Therapy Pilot Study

10 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT04744935 2026-03-24

Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

40 enrolled

Carcinoma, Basal Cell

NCT05929664 2026-03-24

Cemiplimab Plus Fianlimab for the Treatment of Locally Advanced Head and Neck Basal Cell Carcinoma Before Surgery

70 enrolled

Phase NA Not yet recruiting

Carcinoma, Basal Cell

NCT07482956 2026-03-19

BCC-One-Stop-Study

290 enrolled

Phase NA Not yet recruiting

Carcinoma, Basal Cell, Skin Neoplasms

NCT07241585 2026-03-17

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

54 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT06981325 2026-03-11

CEMI-first

34 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT07227350 2026-03-10

L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)

180 enrolled

Carcinoma, Basal Cell

NCT07227870 2026-03-09

L19IL2/TNF in Patients With Basal Cell Carcinoma

92 enrolled

Phase EARLY_PHASE1 Recruiting

Carcinoma, Basal Cell

NCT07144384 2026-02-13

Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma

40 enrolled

Carcinoma, Basal Cell

NCT06624475 2026-02-05

NEON

30 enrolled

Carcinoma, Basal Cell

NCT07182240 2026-02-04

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

Phase NA Recruiting

Phase NA Not yet recruiting

Carcinoma, Basal Cell

NCT07384078 2026-02-03

HIFUvsCRYO

294 enrolled

Bowen's Disease, Carcinoma, Basal Cell

NCT06623201 2026-01-29

Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

Phase 1 Recruiting

20 enrolled

Carcinoma, Basal Cell

NCT06422936 2026-01-26

SPOTLIGHT204

Carcinoma, Basal Cell

NCT03889912 2026-01-21

Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

Phase 1 Completed

97 enrolled

Phase 1 Active not recruiting

Carcinoma, Basal Cell

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT07311070 2026-01-06

Treatment of Basal Cell Carcinoma (BCC) of the Skin, of the Morpheiform, Infiltrative, and Noduloulcerative Types in Inoperable Patients and Not Suitable for Radiotherapy Using Formulated Methylene Blue

Phase 3 Enrolling by invitation

20 enrolled

Carcinoma, Basal Cell

NCT03509467 2025-12-19

Using MC1R Genotype to Impact Melanoma Risk Behavior

2,054 enrolled 92 charts

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms, Neoplasms, Basal Cell, Neoplasms, Squamous Cell

NCT03534947 2025-12-16

SONIB

16 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT03886181 2025-12-08

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Phase NA Terminated

2 enrolled

BreastDermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04916002 2025-12-05

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Phase 2 Terminated

77 enrolled 18 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Carcinoma, Merkel Cell, Triple Negative Breast Neoplasms

NCT05859074 2025-12-03

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Phase 1 Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Hemangiosarcoma, Melanoma, Neoplasm Metastasis, Neoplasms, Paget Disease, Extramammary, Sarcoma, Kaposi, Skin Neoplasms, Carcinoma, Merkel Cell, Adenocarcinoma, Sebaceous, Carcinoma, Skin Appendage

NCT03889899 2025-12-02

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.

Phase NA Recruiting

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04540588 2025-12-02

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

2 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Recurrence, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05935995 2025-11-28

HISTOBLOC

42 enrolled

DermatologicHead & Neck

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell

NCT05020912 2025-11-26

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

28 enrolled