Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 2 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 10Sarcoma 2Genitourinary 2Dermatologic 2CNS 2Thoracic 1Lymphoid 1Head & Neck 1Breast 1

Conditions

Melanoma 9Carcinoma, Renal Cell 4Sarcoma 3Prostatic Neoplasms 3Keratosis, Actinic 3Osteosarcoma 2Neoplasm Metastasis 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Carcinoma, Hepatocellular 2Breast Neoplasms 2Wilms Tumor 1Uveal Melanoma 1Tongue Neoplasms 1Thyroid Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Small Cell Lung Carcinoma 1Skin Neoplasms 1Sarcoma, Ewing 1Salivary Gland Neoplasms 1Rhabdomyosarcoma 1Pancreatic Neoplasms 1Pain 1Ovarian Neoplasms 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Neoplasms, Unknown Primary 1Neoplasms 1Kidney Neoplasms 1Intraocular Lymphoma 1

Interventions

pembrolizumab 19Nivolumab 16Cyclophosphamide 9Specimen Handling 7Ipilimumab 7atezolizumab 6fludarabine 5Magnetic Resonance Spectroscopy 5durvalumab 3avelumab 3X-Rays 3Biopsy 3ulixertinib 2sargramostim 2poly ICLC 2lenvatinib 2epacadostat 2enzalutamide 2cemiplimab 2cabozantinib 2budigalimab 2aldesleukin 2Trastuzumab 2Sirolimus 2Paclitaxel 2Melphalan 2Interleukin-2 2Immunoglobulin G 2Immune Checkpoint Inhibitors 2Docetaxel 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Carcinoma, Hepatocellular × Cryosurgery × Dermatologic × Clear all
NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Children's National Research Institute

Phase 2 Completed
5 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase EARLY_PHASE1 Terminated
19 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

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