Clinical Trials

Carcinoma, Squamous Cell, Skin Neoplasms

NCT07257094 2026-03-31

Nasal Reconstruction FACE-Q : French Validation of the Nasal Reconstruction FACE-Q Questionnaire for Reconstruction/Rehabilitation Following Nasal Skin Cancer

Recruiting

346 enrolled

Phase NA Not yet recruiting

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT07241585 2026-03-17

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

54 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmOther solid neoplasmPlasma cellThoracic

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT07403630 2026-02-17

IT-TCP POS

Phase NA Recruiting

300 enrolled

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Squamous Cell, Melanoma, Multiple Myeloma, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05863052 2026-02-10

Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population

Active not recruiting

72 enrolled

DermatologicGastrointestinalGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis

NCT05843994 2026-02-03

Artificial Intelligence Patient App for RDEB SCCs

Active not recruiting

20 enrolled

Congenital Abnormalities, Carcinoma, Squamous Cell, Epidermolysis Bullosa, Skin Abnormalities, Skin Diseases, Skin Diseases, Vesiculobullous, Skin Diseases, Genetic, Skin Neoplasms, Epidermolysis Bullosa Dystrophica, Genetic Diseases, Inborn

NCT05482880 2026-01-06

Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region

Completed

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Skin Neoplasms, Patient Satisfaction

NCT00133887 2025-12-26

TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients

Phase 3 Completed

77 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

Carcinoma, Squamous Cell, Skin Neoplasms

NCT07285044 2025-12-22

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Phase 2 Recruiting

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT03509467 2025-12-19

Using MC1R Genotype to Impact Melanoma Risk Behavior

Phase NA Completed

2,054 enrolled 92 charts

DermatologicHead & NeckSarcoma

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms, Neoplasms, Basal Cell, Neoplasms, Squamous Cell

NCT05859074 2025-12-03

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Phase 1 Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Hemangiosarcoma, Melanoma, Neoplasm Metastasis, Neoplasms, Paget Disease, Extramammary, Sarcoma, Kaposi, Skin Neoplasms, Carcinoma, Merkel Cell, Adenocarcinoma, Sebaceous, Carcinoma, Skin Appendage

NCT07201012 2025-11-17

SMT-SL

Phase NA Not yet recruiting

150 enrolled

DermatologicGastrointestinal

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Colorectal Neoplasms, Hereditary Nonpolyposis, Skin Neoplasms, Muir-Torre Syndrome

NCT07010692 2025-09-17

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

Phase 1/2 Recruiting

100 enrolled

Phase NA Active not recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Skin Neoplasms

NCT07177638 2025-09-17

A Community-based Educational Initiative to Raise Awareness of Melanoma and Other Skin Cancers.

45 enrolled

Phase 2 Active not recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms

NCT05574101 2025-08-08

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

34 enrolled

Phase 1 Active not recruiting

Carcinoma, Squamous Cell, Skin Neoplasms

NCT03336606 2025-07-10

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

35 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT04099446 2025-06-05

A Non-Interventional Pilot Study to Explore the Skin Microbes in Skin Cancer

Withdrawn

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms

NCT04329221 2025-05-07

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

Phase 2 Withdrawn

Carcinoma, Squamous Cell, Skin Neoplasms, Keratosis, Actinic

NCT04642287 2025-05-07

Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

Phase 2 Withdrawn

Carcinoma, Squamous Cell, Skin Neoplasms, Keratosis, Actinic

NCT05648604 2025-05-04

H4H2-AZ

Phase NA Completed

29 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Motor Activity, Skin Neoplasms

NCT06046625 2025-04-04

Needs and Preferences of Patients With Head-neck Cutaneous SCC

Active not recruiting

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Skin Neoplasms, Patient Satisfaction, Patient Preference

NCT06384924 2025-03-27

Raman Spectroscopy and Skin Cancer

Recruiting

20 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Skin Neoplasms

NCT05955924 2025-02-21

SPRINTR

Phase 3 Recruiting

396 enrolled

DermatologicGastrointestinalGenitourinarySarcomaThoracic

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT03190174 2025-02-17

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Phase 1/2 Completed

34 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Chordoma, Carcinoma, Hepatocellular, Melanoma, Sarcoma, Sarcoma, Ewing, Colorectal Neoplasms, Desmoid Tumors, Perivascular Epithelioid Cell Neoplasms

NCT06159842 2025-02-12

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC)

Phase 2 Completed

32 enrolled

DermatologicGynecologic

Squamous Intraepithelial Lesions, Carcinoma, Squamous Cell, Skin Neoplasms

NCT05202860 2025-01-22

VAXAK

Phase 2 Active not recruiting

70 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Keratosis, Actinic

NCT03714828 2024-10-09

Study of TVEC in Patients With Cutaneous Squamous Cell Cancer

Phase 2 Completed

11 enrolled 15 charts

Carcinoma, Squamous Cell, Keratoacanthoma, Skin Neoplasms

NCT06577311 2024-08-29

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

Phase 2 Recruiting

20 enrolled

DermatologicGynecologic

Squamous Intraepithelial Lesions, Carcinoma, Squamous Cell, Skin Neoplasms

NCT01980264 2024-08-21

Harmonics-based in Vivo Optical Virtual Biopsy

Phase NA Recruiting

500 enrolled

Phase NA Not yet recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Diabetes Mellitus, Melanoma, Skin Neoplasms

NCT06493786 2024-07-10

SCENT-SKIN-001

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT04814953 2024-05-09

HRQoL Keratinocyte Carcinomas

Enrolling by invitation

2,400 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Keratosis, Actinic

NCT04410874 2024-03-07

MUSIC-01

Phase 1/2 Terminated

1 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Skin Neoplasms

NCT05942794 2024-02-28

Identification of Oral Lesions Through an Autofluorescence System

200 enrolled

Carcinoma, Squamous Cell, Keratosis, Leukoplakia, Oral, Lichen Planus, Mouth Diseases, Mouth Neoplasms, Lichen Planus, Oral

NCT06227416 2024-01-26

Skin Tumor Biomarkers by Mass Spectrometry Imaging

300 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Skin Neoplasms

NCT01586767 2023-09-21

Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy

45 enrolled

CNSDermatologic

Sinonasal undifferentiated carcinoma, Carcinoma, Squamous Cell, Carcinoma, Adenoid Cystic, Fistula, Melanoma, Carcinoma, Mucoepidermoid, Esthesioneuroblastoma, Olfactory

NCT05845632 2023-08-16

Time to Treatment and Disease-free Survival of Patients With High-risk Head-neck Cutaneous Squamous Cell Carcinoma

Unknown

965 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Squamous Cell, Neoplasm Metastasis, Recurrence, Skin Neoplasms

NCT04688749 2023-07-25

DermaSense

Terminated

50 enrolled

DermatologicSarcoma

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Carcinosarcoma, Dysplastic Nevus Syndrome, Melanoma, Neoplasms, Keratosis, Seborrheic, Hutchinson's Melanotic Freckle

NCT03982212 2023-05-19

A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors

Phase 1 Unknown

10 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT03769285 2023-04-06

SPRINTR-Pilot

Phase 2 Unknown

BreastDermatologicGastrointestinalGynecologicHead & Neck

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT02997553 2023-01-09

GASVERT

Phase 3 Completed

744 enrolled

Anus Neoplasms, Breast Neoplasms, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Rectal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT00540566 2022-10-20

Optical Biopsy of Human Skin in Conjunction With Laser Treatment

Completed

113 enrolled

DermatologicSarcoma

Burns, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Dysplastic Nevus Syndrome, Hemangioma, Melanoma, Osteitis Deformans, Sarcoma, Kaposi, Carcinoma, Merkel Cell, Keratosis, Seborrheic, Histiocytoma, Benign Fibrous, Port-Wine Stain, Scleroderma, Diffuse

NCT02218164 2022-10-07

Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinoma

Phase 2 Completed

8 enrolled 11 charts

Carcinoma, Squamous Cell, Neoplasm Metastasis, Skin Neoplasms

NCT05402046 2022-06-02

CAMELLIA

605 enrolled

Bowen's Disease, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Nevus, Nevus, Pigmented, Nevus, Epithelioid and Spindle Cell, Nevus, Halo

NCT05340543 2022-04-22

DERMOCTAV

Unknown

150 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Melanoma, Skin Neoplasms

NCT03458117 2022-03-18

20139157 T-VEC

Phase 1 Completed

26 enrolled

DermatologicLymphoid

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Carcinoma, Merkel Cell, Lymphoma, T-Cell, Cutaneous

NCT00793169 2021-12-06

Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery

Completed

19 enrolled 4 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT05072327 2021-10-08

Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors.

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Eyelid Neoplasms, Adenocarcinoma, Sebaceous

NCT04628806 2021-05-14

HSP70CTC

Unknown