Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 5Genitourinary 3CNS 3Gastrointestinal 2Dermatologic 2Other solid neoplasm 1Lymphoid 1

Conditions

Melanoma 317Carcinoma, Non-Small-Cell Lung 72Skin Neoplasms 65Carcinoma, Renal Cell 48Lung Neoplasms 45Breast Neoplasms 45Colorectal Neoplasms 42Carcinoma, Basal Cell 41Neoplasms 40Neoplasm Metastasis 40Squamous Cell Carcinoma of Head and Neck 36Uveal Melanoma 33Ovarian Neoplasms 33Carcinoma, Merkel Cell 32Sarcoma 31Lymphoma, T-Cell, Cutaneous 31Pancreatic Neoplasms 26Prostatic Neoplasms 24Head and Neck Neoplasms 22Stomach Neoplasms 21Thyroid Neoplasms 20Urinary Bladder Neoplasms 19Carcinoma, Hepatocellular 19Uterine Cervical Neoplasms 18Esophageal Neoplasms 18Carcinoma, Squamous Cell 18Mycosis Fungoides 16Carcinoma, Transitional Cell 16Brain Neoplasms 16Recurrence 15

Interventions

pembrolizumab 1fludarabine phosphate 1fludarabine 1Mesna 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Desmoplastic Small Round Cell Tumor × Dermatologic × 90 days × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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