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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 3CNS 2Genitourinary 1Gastrointestinal 1Dermatologic 1

Conditions

Melanoma 62Lymphoma, T-Cell, Cutaneous 42Lymphoma, Follicular 37Lymphoma, B-Cell, Marginal Zone 37Leukemia, Lymphocytic, Chronic, B-Cell 37Precursor Cell Lymphoblastic Leukemia-Lymphoma 36Lymphoma, Non-Hodgkin 36Lymphoma, Mantle-Cell 35Sezary Syndrome 34Mycosis Fungoides 34Lymphoma, Large B-Cell, Diffuse 34Hodgkin Disease 33Multiple Myeloma 32Lymphoma, Large-Cell, Immunoblastic 32Leukemia, Myeloid, Acute 32Burkitt Lymphoma 32Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Congenital Abnormalities 30Leukemia, Myeloid, Accelerated Phase 27Leukemia, Myeloid, Chronic-Phase 26Waldenstrom Macroglobulinemia 25Lymphoma, Large-Cell, Anaplastic 25Lymphoma 25Myeloproliferative Disorders 24Lymphoma, Extranodal NK-T-Cell 24Leukemia 23Immunoblastic Lymphadenopathy 23Leukemia, Myelomonocytic, Chronic 21Recurrence 20Myelodysplastic Syndromes 19

Interventions

pembrolizumab 1ganitumab 1fludarabine phosphate 1fludarabine 1Mesna 1Mass Spectrometry 1Immunologic Techniques 1Cyclophosphamide 1Chromatography, High Pressure Liquid 1Biopsy 1BI 2536 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Desmoplastic Small Round Cell Tumor × fludarabine phosphate × Dermatologic × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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