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Phase

Phase NA 2Phase 1/2 1Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 6CNS 5Plasma cell 4Other solid neoplasm 2Other hematologic neoplasm 2Lymphoid 2Gastrointestinal 2Sarcoma 1Gynecologic 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Melanoma 778Carcinoma, Non-Small-Cell Lung 198Lymphoma, T-Cell, Cutaneous 171Carcinoma, Renal Cell 139Neoplasms 130Mycosis Fungoides 120Breast Neoplasms 114Lymphoma, Large B-Cell, Diffuse 112Colorectal Neoplasms 111Lymphoma, Non-Hodgkin 110Sezary Syndrome 109Lymphoma, Follicular 107Neoplasm Metastasis 105Lymphoma 103Leukemia, Lymphocytic, Chronic, B-Cell 103Lymphoma, Mantle-Cell 100Lymphoma, B-Cell, Marginal Zone 98Hodgkin Disease 98Precursor Cell Lymphoblastic Leukemia-Lymphoma 97Burkitt Lymphoma 94Squamous Cell Carcinoma of Head and Neck 92Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 92Lymphoma, Large-Cell, Immunoblastic 86Lymphoma, Large-Cell, Anaplastic 86Ovarian Neoplasms 84Lung Neoplasms 80Immunoblastic Lymphadenopathy 79Sarcoma 67Pancreatic Neoplasms 65Head and Neck Neoplasms 64

Interventions

tremelimumab 1durvalumab 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Disease Progression × Dermatologic × Clear all
NCT02586987 2019-11-18

A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours

AstraZeneca

Phase 1 Completed
58 enrolled
BreastDermatologicGastrointestinalThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms, Disease Progression

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