Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Active not recruiting 2

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 64Sarcoma 20Lymphoid 14Gastrointestinal 14Genitourinary 13Myeloid 12Endocrine 2Dermatologic 2NET 1Head & Neck 1

Conditions

Melanoma 783Carcinoma, Non-Small-Cell Lung 170Skin Neoplasms 154Neoplasms 106Neoplasm Metastasis 100Colorectal Neoplasms 97Carcinoma, Renal Cell 95Uveal Melanoma 92Breast Neoplasms 88Squamous Cell Carcinoma of Head and Neck 85Carcinoma, Basal Cell 83Lung Neoplasms 81Ovarian Neoplasms 79Sarcoma 67Lymphoma, T-Cell, Cutaneous 66Carcinoma, Merkel Cell 66Stomach Neoplasms 58Pancreatic Neoplasms 58Head and Neck Neoplasms 55Carcinoma, Hepatocellular 53Uterine Cervical Neoplasms 52Urinary Bladder Neoplasms 50Esophageal Neoplasms 44Prostatic Neoplasms 43Triple Negative Breast Neoplasms 42Endometrial Neoplasms 41Carcinoma, Squamous Cell 39Brain Neoplasms 39Carcinoma, Transitional Cell 37Lymphoma 35

Interventions

tipifarnib 1dostarlimab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Ependymoma × Dermatologic × 1 year × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT06521567 2025-11-12

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

GlaxoSmithKline

Phase 1/2 Active not recruiting
83 enrolled
CNSDermatologicGastrointestinalLymphoidSarcoma

Fibrolamellar hepatocellular carcinoma, Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Melanoma, Rhabdomyosarcoma, Osteosarcoma, Hepatoblastoma

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