Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 67Thoracic 15Head & Neck 12Gynecologic 10Breast 9Genitourinary 6Other solid neoplasm 2Dermatologic 2Sarcoma 1Plasma cell 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Melanoma 346Carcinoma, Non-Small-Cell Lung 81Skin Neoplasms 71Carcinoma, Renal Cell 51Lung Neoplasms 49Neoplasm Metastasis 47Breast Neoplasms 45Colorectal Neoplasms 44Neoplasms 42Carcinoma, Basal Cell 42Uveal Melanoma 38Squamous Cell Carcinoma of Head and Neck 37Carcinoma, Merkel Cell 36Ovarian Neoplasms 35Sarcoma 31Lymphoma, T-Cell, Cutaneous 31Pancreatic Neoplasms 26Prostatic Neoplasms 24Carcinoma, Hepatocellular 23Stomach Neoplasms 21Head and Neck Neoplasms 21Uterine Cervical Neoplasms 20Urinary Bladder Neoplasms 20Thyroid Neoplasms 20Esophageal Neoplasms 19Brain Neoplasms 18Carcinoma, Squamous Cell 17Mycosis Fungoides 16Carcinoma, Transitional Cell 16Triple Negative Breast Neoplasms 15

Interventions

nazartinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Esophageal Squamous Cell Carcinoma × Dermatologic × 90 days × Clear all
NCT03114319 2026-04-16

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Novartis

Phase 1 Terminated
227 enrolled
DermatologicGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Melanoma, Noonan Syndrome

NCT04140500 2026-03-18

Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors

Hoffmann-La Roche

Phase 1/2 Active not recruiting
170 enrolled
DermatologicGastrointestinalThoracic

Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Melanoma

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