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Phase

Phase 1 17Phase 2 5Phase 1/2 4Phase EARLY_PHASE1 2Phase 2/3 2Phase 4 1Phase 3 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 9Other hematologic neoplasm 4Gastrointestinal 3Thoracic 2Plasma cell 2Myeloid 2Lymphoid 2Head & Neck 2Gynecologic 2Endocrine 2Dermatologic 2Sarcoma 1

Conditions

Melanoma 22Neoplasms 6Skin Neoplasms 4Neoplasm Metastasis 4Colorectal Neoplasms 4Uveal Melanoma 3Ovarian Neoplasms 3Neoplasms by Site 3Neoplasms by Histologic Type 3Lung Neoplasms 3Keratosis, Actinic 3Hematologic Neoplasms 3Head and Neck Neoplasms 3Carcinoma, Basal Cell 3Breast Neoplasms 3Sezary Syndrome 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Pancreatic Neoplasms 2Mycosis Fungoides 2Lymphoproliferative Disorders 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma 2Glioma 2Carcinoma, Non-Small-Cell Lung 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Urogenital Neoplasms 1Urinary Bladder Neoplasms 1Thyroid Carcinoma, Anaplastic 1

Interventions

entrectinib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Glioma × Dermatologic × Clear all
NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05770544 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicLymphoidOther hematologic neoplasm

Brain Neoplasms, Glioma, Lymphoproliferative Disorders, Melanoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Hematologic Neoplasms

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