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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Melanoma 62Lymphoma, T-Cell, Cutaneous 42Lymphoma, Follicular 37Lymphoma, B-Cell, Marginal Zone 37Leukemia, Lymphocytic, Chronic, B-Cell 37Precursor Cell Lymphoblastic Leukemia-Lymphoma 36Lymphoma, Non-Hodgkin 36Lymphoma, Mantle-Cell 35Sezary Syndrome 34Mycosis Fungoides 34Lymphoma, Large B-Cell, Diffuse 34Hodgkin Disease 33Multiple Myeloma 32Lymphoma, Large-Cell, Immunoblastic 32Leukemia, Myeloid, Acute 32Burkitt Lymphoma 32Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Congenital Abnormalities 30Leukemia, Myeloid, Accelerated Phase 27Leukemia, Myeloid, Chronic-Phase 26Waldenstrom Macroglobulinemia 25Lymphoma, Large-Cell, Anaplastic 25Lymphoma 25Myeloproliferative Disorders 24Lymphoma, Extranodal NK-T-Cell 24Leukemia 23Immunoblastic Lymphadenopathy 23Leukemia, Myelomonocytic, Chronic 21Recurrence 20Myelodysplastic Syndromes 19

Interventions

tipifarnib 1pembrolizumab 1fludarabine phosphate 1fludarabine 1dostarlimab 1X-Rays 1Specimen Handling 1Phantoms, Imaging 1Nivolumab 1Mesna 1Ipilimumab 1Cyclophosphamide 1Cryotherapy 1Cryosurgery 1Bone Density 1Absorptiometry, Photon 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Hepatoblastoma × fludarabine phosphate × Dermatologic × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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