Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 3Terminated 2Completed 2

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 9Gastrointestinal 6Thoracic 5Head & Neck 3Lymphoid 2Gynecologic 2Genitourinary 2Dermatologic 2CNS 2Sarcoma 1Classical hematology 1

Conditions

Melanoma 1486Lymphoma, T-Cell, Cutaneous 313Skin Neoplasms 267Keratosis, Actinic 249Mycosis Fungoides 224Sezary Syndrome 216Lymphoma, Non-Hodgkin 206Leukemia, Lymphocytic, Chronic, B-Cell 200Lymphoma, Large B-Cell, Diffuse 198Lymphoma, Follicular 196Neoplasms 194Precursor Cell Lymphoblastic Leukemia-Lymphoma 192Lymphoma, B-Cell, Marginal Zone 192Lymphoma, Mantle-Cell 191Hodgkin Disease 191Carcinoma, Basal Cell 190Breast Neoplasms 185Burkitt Lymphoma 184Lymphoma 182Lymphoma, Large-Cell, Immunoblastic 177Carcinoma, Non-Small-Cell Lung 150Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 140Lymphoma, Large-Cell, Anaplastic 137Multiple Myeloma 133Carcinoma, Renal Cell 128Immunoblastic Lymphadenopathy 126Uveal Melanoma 125Neoplasm Metastasis 120Leukemia, Myeloid, Acute 113Waldenstrom Macroglobulinemia 103

Interventions

binimetinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Hereditary Sensory and Autonomic Neuropathies × Dermatologic × Clear all
NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Revolution Medicines, Inc.

Phase 1 Completed
58 enrolled
DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT01320085 2024-01-24

A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma

Pfizer

Phase 2 Completed
183 enrolled 35 charts
Dermatologic

Melanoma, Hereditary Sensory and Autonomic Neuropathies

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