Announcements Trials
Browse Landscape

Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 27Sarcoma 15Genitourinary 12Gastrointestinal 10Myeloid 9Lymphoid 9Endocrine 5Head & Neck 3Dermatologic 2Other solid neoplasm 1NET 1

Conditions

Melanoma 112Carcinoma, Non-Small-Cell Lung 26Skin Neoplasms 20Colorectal Neoplasms 17Sarcoma 15Lung Neoplasms 15Carcinoma, Renal Cell 15Breast Neoplasms 14Squamous Cell Carcinoma of Head and Neck 13Pancreatic Neoplasms 13Ovarian Neoplasms 13Carcinoma, Merkel Cell 12Urinary Bladder Neoplasms 11Prostatic Neoplasms 11Neoplasms 11Carcinoma, Basal Cell 11Stomach Neoplasms 10Neoplasm Metastasis 10Head and Neck Neoplasms 10Carcinoma, Hepatocellular 10Uterine Cervical Neoplasms 8Thyroid Neoplasms 8Lymphoma, T-Cell, Cutaneous 8Mycosis Fungoides 7Esophageal Neoplasms 7Brain Neoplasms 7Recurrence 6Lymphoma, Large-Cell, Anaplastic 6Lymphoma 6Gastrointestinal Neoplasms 6

Interventions

tipifarnib 1fludarabine phosphate 1fludarabine 1Mesna 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neuroblastoma × Dermatologic × 30 days × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

Data powered by HemOnc (CC BY 4.0) Colophon âš¡