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Phase

Phase NA 2Phase 1 2Phase 1/2 1

Status

Unknown 1Terminated 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 6Gastrointestinal 6Thoracic 5Dermatologic 2Breast 2Sarcoma 1Gynecologic 1Genitourinary 1

Conditions

Melanoma 778Carcinoma, Non-Small-Cell Lung 198Lymphoma, T-Cell, Cutaneous 171Carcinoma, Renal Cell 139Neoplasms 130Mycosis Fungoides 120Breast Neoplasms 114Lymphoma, Large B-Cell, Diffuse 112Colorectal Neoplasms 111Lymphoma, Non-Hodgkin 110Sezary Syndrome 109Lymphoma, Follicular 107Neoplasm Metastasis 105Lymphoma 103Leukemia, Lymphocytic, Chronic, B-Cell 103Lymphoma, Mantle-Cell 100Lymphoma, B-Cell, Marginal Zone 98Hodgkin Disease 98Precursor Cell Lymphoblastic Leukemia-Lymphoma 97Burkitt Lymphoma 94Squamous Cell Carcinoma of Head and Neck 92Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 92Lymphoma, Large-Cell, Immunoblastic 86Lymphoma, Large-Cell, Anaplastic 86Ovarian Neoplasms 84Lung Neoplasms 80Immunoblastic Lymphadenopathy 79Sarcoma 67Pancreatic Neoplasms 65Head and Neck Neoplasms 64

Interventions

nazartinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Noonan Syndrome × Dermatologic × Clear all
NCT03114319 2026-04-16

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Novartis

Phase 1 Terminated
227 enrolled
DermatologicGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Melanoma, Noonan Syndrome

NCT03634982 2022-09-01

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

Revolution Medicines, Inc.

Phase 1 Unknown
133 enrolled
DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Noonan Syndrome, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

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