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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Melanoma 17Lung Neoplasms 6Head and Neck Neoplasms 6Pancreatic Neoplasms 5Neoplasms 5Colorectal Neoplasms 5Breast Neoplasms 5Ovarian Neoplasms 4Kidney Neoplasms 4Waldenstrom Macroglobulinemia 3Stomach Neoplasms 3Skin Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Mycosis Fungoides 3Multiple Myeloma 3Lymphoma, T-Cell, Cutaneous 3Lymphoma, Non-Hodgkin 3Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, Follicular 3Lymphoma, B-Cell, Marginal Zone 3Liver Neoplasms 3Glioblastoma 3Esophageal Neoplasms 3Cholangiocarcinoma 3Uterine Cervical Neoplasms 2Sezary Syndrome 2Sarcoma 2Lymphoma, T-Cell, Peripheral 2Lymphoma, Large-Cell, Anaplastic 2

Interventions

pembrolizumab 4motexafin gadolinium 1cabozantinib 1Vorinostat 1Taxes 1Specimen Handling 1Ritonavir 1Radiotherapy 1Pemetrexed 1Paclitaxel 1Nivolumab 1Magnetic Resonance Spectroscopy 1Indinavir 1Drug Therapy 1Doxorubicin 1Cisplatin 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Dermatologic × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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