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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 2Genitourinary 2Gastrointestinal 2CNS 2Other solid neoplasm 1Dermatologic 1

Conditions

Melanoma 5Wilms Tumor 2Sarcoma 2Osteosarcoma 2Neoplasms 2Stomach Neoplasms 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Neurofibrosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Neoplasms, Germ Cell and Embryonal 1Meningeal Neoplasms 1Lymphoma, T-Cell, Cutaneous 1Lymphoma 1Leukemia, Myeloid, Acute 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Biphenotypic, Acute 1Leukemia, B-Cell 1Leukemia 1Hodgkin Disease 1Hepatoblastoma 1Hematologic Diseases 1Gallbladder Neoplasms 1Esophageal Neoplasms 1

Interventions

Nivolumab 3fludarabine 2Ipilimumab 2tipifarnib 1technetium-diethylenetriaminepentaacetic acid-mannosyl-dextran 1pembrolizumab 1iso-sulfan blue 1fludarabine phosphate 1dostarlimab 1bempegaldesleukin 1Stem Cell Transplantation 1Sirolimus 1Mesna 1Melphalan 1Mass Spectrometry 1LY2940680 1Immunologic Techniques 1Cyclophosphamide 1Cryotherapy 1Cryosurgery 1Chromatography, High Pressure Liquid 1CTLA-4 Antigen 1Busulfan 1BI 2536 1Alemtuzumab 1Albumin-Bound Paclitaxel 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Rhabdomyosarcoma × Mesna × Dermatologic × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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