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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 4Genitourinary 2Gastrointestinal 2CNS 2Other solid neoplasm 1Dermatologic 1

Conditions

Melanoma 136Lymphoma, T-Cell, Cutaneous 45Lymphoma, Non-Hodgkin 37Lymphoma, Follicular 36Precursor Cell Lymphoblastic Leukemia-Lymphoma 35Lymphoma, Large B-Cell, Diffuse 35Lymphoma, Large-Cell, Immunoblastic 34Leukemia, Lymphocytic, Chronic, B-Cell 34Lymphoma, Mantle-Cell 33Lymphoma, B-Cell, Marginal Zone 33Burkitt Lymphoma 33Lymphoma 32Leukemia, Myeloid, Acute 32Hodgkin Disease 31Mycosis Fungoides 30Sezary Syndrome 29Multiple Myeloma 28Leukemia, Myeloid, Accelerated Phase 26Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 24Neoplasm Metastasis 24Leukemia, Myeloid, Chronic-Phase 24Leukemia 23Myelodysplastic Syndromes 22Lymphoma, Large-Cell, Anaplastic 22Congenital Abnormalities 22Blast Crisis 22Skin Neoplasms 20Immunoblastic Lymphadenopathy 20Myeloproliferative Disorders 19Recurrence 18

Interventions

pembrolizumab 1fludarabine phosphate 1fludarabine 1Mesna 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Sarcoma, Clear Cell × Cyclophosphamide × Dermatologic × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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