Announcements Trials
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Phase

Phase 1 8Phase 1/2 3Phase 2 2

Status

Unknown 1Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 18CNS 5Gynecologic 4Thoracic 3Lymphoid 3Gastrointestinal 3Dermatologic 3Other solid neoplasm 2Plasma cell 1Other hematologic neoplasm 1NET 1Genitourinary 1Endocrine 1Breast 1

Conditions

Melanoma 426Carcinoma, Non-Small-Cell Lung 92Neoplasm Metastasis 69Neoplasms 60Carcinoma, Renal Cell 54Lymphoma, T-Cell, Cutaneous 52Ovarian Neoplasms 46Squamous Cell Carcinoma of Head and Neck 42Breast Neoplasms 40Colorectal Neoplasms 38Stomach Neoplasms 37Skin Neoplasms 35Lymphoma 32Uveal Melanoma 31Mycosis Fungoides 31Carcinoma, Merkel Cell 31Triple Negative Breast Neoplasms 29Lung Neoplasms 29Sezary Syndrome 28Lymphoma, Non-Hodgkin 28Lymphoma, Follicular 27Hodgkin Disease 27Pancreatic Neoplasms 26Uterine Cervical Neoplasms 25Sarcoma 25Lymphoma, Large B-Cell, Diffuse 24Leukemia, Lymphocytic, Chronic, B-Cell 24Lymphoma, B-Cell, Marginal Zone 23Carcinoma, Hepatocellular 23Lymphoma, Mantle-Cell 22

Interventions

Cyclophosphamide 2aldesleukin 1Leukapheresis 1Interleukin-2 1Injections 1Immunotherapy, Adoptive 1Decitabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Sarcoma, Synovial × Dermatologic × Clear all
NCT05296564 2025-10-02

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Hadassah Medical Organization

Phase 1/2 Recruiting
3 enrolled
BreastCNSDermatologicGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Sarcoma, Synovial, Triple Negative Breast Neoplasms

NCT02650986 2025-06-17

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Roswell Park Cancer Institute

Phase 1/2 Active not recruiting
15 enrolled 12 charts
DermatologicGynecologicSarcoma

Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT03638206 2019-12-11

Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies

Shenzhen BinDeBio Ltd.

Phase 1/2 Unknown
73 enrolled
CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

Burkitt Lymphoma, Carcinoma, Renal Cell, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Leukemia, Myeloid, Lung Neoplasms, Lymphoma, Melanoma, Mesothelioma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Sarcoma, Synovial, Colorectal Neoplasms

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