Announcements Trials
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Phase

Phase 2/3 1Phase 1 1

Status

Suspended 1Recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 24Endocrine 24Thoracic 6Gynecologic 6Gastrointestinal 3CNS 3Plasma cell 2Other hematologic neoplasm 2NET 2Myeloid 2Dermatologic 2Sarcoma 1Lymphoid 1Genitourinary 1Breast 1

Conditions

Melanoma 791Carcinoma, Non-Small-Cell Lung 171Skin Neoplasms 154Neoplasms 107Neoplasm Metastasis 100Colorectal Neoplasms 96Carcinoma, Renal Cell 96Uveal Melanoma 92Breast Neoplasms 88Squamous Cell Carcinoma of Head and Neck 85Carcinoma, Basal Cell 85Lung Neoplasms 80Ovarian Neoplasms 79Lymphoma, T-Cell, Cutaneous 67Carcinoma, Merkel Cell 67Sarcoma 66Pancreatic Neoplasms 59Stomach Neoplasms 58Head and Neck Neoplasms 55Carcinoma, Hepatocellular 54Uterine Cervical Neoplasms 53Urinary Bladder Neoplasms 50Triple Negative Breast Neoplasms 44Esophageal Neoplasms 44Prostatic Neoplasms 43Endometrial Neoplasms 42Carcinoma, Squamous Cell 39Brain Neoplasms 39Carcinoma, Transitional Cell 37Lymphoma 34

Interventions

dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × Dermatologic × 1 year × Clear all
NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT04418167 2025-09-03

JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

JS InnoPharm, LLC

Phase 1 Suspended
71 enrolled
DermatologicEndocrineHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Thyroid Carcinoma, Anaplastic

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