Announcements Trials
Browse Landscape

Phase

Phase 2 6Phase 3 1

Status

Completed 5Terminated 2

Sponsor Class

NIH 4INDUSTRY 2OTHER 1

Study Type

Interventional 7

Sponsor

Cancer Type

Thoracic 10Gastrointestinal 7Dermatologic 7CNS 5Head & Neck 4Tumor-Agnostic 3Other solid neoplasm 3Endocrine 3Breast 3Sarcoma 2Lymphoid 2Plasma cell 1Other hematologic neoplasm 1Myeloid 1Gynecologic 1

Conditions

Melanoma 5Uveal Melanoma 2Neoplasm Metastasis 1

Interventions

Ipilimumab 101pembrolizumab 94Nivolumab 87Cyclophosphamide 69fludarabine phosphate 55aldesleukin 52Interleukin-2 39Dacarbazine 35Vemurafenib 31fludarabine 30trametinib 29dabrafenib 29Temozolomide 28Whole-Body Irradiation 21Aminolevulinic Acid 21Carboplatin 20CTLA-4 Antigen 20Bevacizumab 20Radiotherapy 19Peripheral Blood Stem Cell Transplantation 19Radiosurgery 18Tacrolimus 17Mycophenolic Acid 17Paclitaxel 16HhAntag691 163-ingenyl angelate 16Busulfan 15Introns 14Antilymphocyte Serum 14encorafenib 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Has results × AZD 6244 × Dermatologic × Clear all
NCT01256359 2024-08-15

DOC-MEK

University of Oxford

Phase 2 Completed
83 enrolled 60 charts
Dermatologic

Melanoma

NCT01143402 2017-07-26

Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye

National Cancer Institute (NCI)

Phase 2 Completed
120 enrolled 8 charts
Dermatologic

Uveal Melanoma

NCT01974752 2017-01-05

SUMIT

AstraZeneca

Phase 3 Completed
152 enrolled 14 charts
Dermatologic

Uveal Melanoma, Neoplasm Metastasis

NCT00936221 2016-03-14

Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients

AstraZeneca

Phase 2 Completed
385 enrolled 11 charts
Dermatologic

Melanoma

NCT00866177 2015-08-11

MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma

National Cancer Institute (NCI)

Phase 2 Completed
167 enrolled 6 charts
Dermatologic

Melanoma

NCT01519427 2014-06-18

Selumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib

National Cancer Institute (NCI)

Phase 2 Terminated
2 enrolled 9 charts
Dermatologic

Melanoma

NCT01166126 2014-05-15

Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

National Cancer Institute (NCI)

Phase 2 Terminated
4 enrolled 7 charts
Dermatologic

Melanoma

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