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Phase

Phase 2 12Phase 3 11Phase 1 7Phase 4 6Phase NA 2Phase EARLY_PHASE1 1Phase 1/2 1

Status

Completed 7

Sponsor Class

INDUSTRY 6OTHER 1

Study Type

Interventional 7

Sponsor

Cancer Type

Dermatologic 7

Conditions

Keratosis, Actinic 7Facies 1

Interventions

pembrolizumab 100Nivolumab 69Cyclophosphamide 67Ipilimumab 66fludarabine 34aldesleukin 29fludarabine phosphate 28Vemurafenib 28Interleukin-2 26trametinib 20Biopsy 20dabrafenib 17Radiotherapy 16Temozolomide 15Cisplatin 15Magnetic Resonance Spectroscopy 14Gemcitabine 14Filgrastim 14atezolizumab 13Specimen Handling 13Carboplatin 13CTLA-4 Antigen 13spartalizumab 12romidepsin 12Paclitaxel 12Bortezomib 11poly ICLC 10cobimetinib 10Peripheral Blood Stem Cell Transplantation 10Oxaliplatin 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 1 × 3-ingenyl angelate × Dermatologic × Clear all
NCT01449513 2025-03-07

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy

LEO Pharma

Phase 1 Completed
24 enrolled 26 charts
Dermatologic

Keratosis, Actinic

NCT01387711 2025-02-24

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology

LEO Pharma

Phase 1 Completed
27 enrolled
Dermatologic

Keratosis, Actinic

NCT02124239 2025-02-24

Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions

LEO Pharma

Phase 1 Completed
79 enrolled
Dermatologic

Keratosis, Actinic

NCT00850681 2015-09-09

A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Peplin

Phase 1 Completed
50 enrolled
Dermatologic

Keratosis, Actinic

NCT00850811 2015-09-09

A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Peplin

Phase 1 Completed
30 enrolled
Dermatologic

Keratosis, Actinic

NCT00544258 2015-02-12

Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005

Peplin

Phase 1 Completed
8 enrolled
Dermatologic

Keratosis, Actinic

NCT01836367 2013-12-31

Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp

Icahn School of Medicine at Mount Sinai

Phase 1 Completed
20 enrolled
Dermatologic

Facies, Keratosis, Actinic

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