Announcements Trials
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Phase

Phase 1 4Phase 2 1Phase 1/2 1

Status

Completed 5Terminated 1

Sponsor Class

OTHER 3INDUSTRY 2FED 1

Study Type

Interventional 6

Sponsor

Cancer Type

Gastrointestinal 11Dermatologic 6Thoracic 5CNS 4Sarcoma 3Other hematologic neoplasm 3Other solid neoplasm 2Genitourinary 2Lymphoid 1Gynecologic 1Breast 1

Conditions

Melanoma 4Uveal Melanoma 3Skin Neoplasms 1Ovarian Neoplasms 1Neoplasms 1Neoplasm Metastasis 1Glioma 1Carcinoma, Hepatocellular 1Carcinoma 1

Interventions

pembrolizumab 339Nivolumab 305Ipilimumab 274Cyclophosphamide 194aldesleukin 148Interleukin-2 110fludarabine phosphate 106trametinib 85Temozolomide 83Dacarbazine 81fludarabine 80dabrafenib 77Radiotherapy 75Biopsy 75Vemurafenib 71Imiquimod 53Bevacizumab 51sargramostim 50Radiosurgery 49Peripheral Blood Stem Cell Transplantation 49Paclitaxel 49Magnetic Resonance Spectroscopy 49Aminolevulinic Acid 49binimetinib 48Carboplatin 48Specimen Handling 47Blood Specimen Collection 47cemiplimab 46Cisplatin 453-ingenyl angelate 45

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
ADI PEG20 × Dermatologic × Clear all
NCT03922880 2025-05-15

Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
9 enrolled
Dermatologic

Uveal Melanoma

NCT00520299 2022-10-25

Study of ADI-PEG 20 in Patients With Advanced Melanoma

Ludwig Institute for Cancer Research

Phase 1/2 Completed
31 enrolled 16 charts
Dermatologic

Melanoma, Neoplasms, Skin Neoplasms

NCT02029690 2020-09-25

TRAP

Polaris Group

Phase 1 Terminated
85 enrolled
CNSDermatologicGastrointestinal

Uveal Melanoma, Carcinoma, Glioma, Carcinoma, Hepatocellular

NCT00450372 2017-02-08

Pegylated Arginine Deiminase in Treating Patients With Metastatic Melanoma That Cannot Be Removed by Surgery

University of Miami

Phase 2 Completed
38 enrolled 9 charts
Dermatologic

Melanoma

NCT01665183 2016-02-25

Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma

Polaris Group

Phase 1 Completed
8 enrolled
DermatologicGynecologic

Uveal Melanoma, Melanoma, Ovarian Neoplasms

NCT00029900 2015-03-25

ADI-PEG in Patients With Metastatic Melanoma

FDA Office of Orphan Products Development

Phase 1 Completed
15 enrolled
Dermatologic

Melanoma, Neoplasm Metastasis

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