Clinical Trials Browser

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Phase 1 Active not recruiting

39 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT06499415 2025-05-11

CALM

Phase 4 Recruiting

232 enrolled

Dermatologic

Keratosis, Actinic

NCT04329221 2025-05-07

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

Phase 2 Withdrawn

Dermatologic

Carcinoma, Squamous Cell, Skin Neoplasms, Keratosis, Actinic

NCT04642287 2025-05-07

Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

Phase 2 Withdrawn

Dermatologic

Carcinoma, Squamous Cell, Skin Neoplasms, Keratosis, Actinic

NCT03167164 2025-02-21

QUILT-3.045: NANT Merkel Cell Carcinoma (MCC) Vaccine: Combination Immunotherapy in Subjects With MCC Who Have Progressed on or After PD-L1 Therapy

Phase 1/2 Withdrawn

Dermatologic

Carcinoma, Merkel Cell

NCT03167177 2025-02-21

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Phase 1/2 Withdrawn

Dermatologic

Melanoma

NCT06712381 2024-12-02

Carac & PDT Combination in the Treatment Of Actinic Keratoses

Phase 1/2 Completed

60 enrolled

Dermatologic

Keratosis, Actinic

NCT03009058 2024-11-25

MODULATE

Phase 1/2 Terminated

2 enrolled 7 charts

DermatologicSarcoma

Melanoma, Neoplasm Metastasis, Sarcoma

NCT06685588 2024-11-12

Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic Keratoses

Phase NA Not yet recruiting

50 enrolled

Dermatologic

Keratosis, Actinic

NCT06150144 2024-01-02

The Efficacy and Safety of Using Intralesional 5-fluorouracil for Basal Cell Carcinoma

Phase 3 Unknown

40 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT05078827 2023-03-14

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Phase 3 Completed

458 enrolled

Dermatologic

Keratosis, Actinic

NCT05740969 2023-02-23

PACKS

Phase 2 Unknown

48 enrolled

Dermatologic

Keratosis, Actinic

NCT02218164 2022-10-07

Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinoma

Phase 2 Completed

8 enrolled 11 charts

Dermatologic

Carcinoma, Squamous Cell, Neoplasm Metastasis, Skin Neoplasms

NCT04875026 2022-09-19

Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial

Phase 4 Completed

146 enrolled

Dermatologic

Keratosis, Actinic

NCT01525329 2022-03-15

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

Phase 3 Terminated

18 enrolled 9 charts

Dermatologic

Keratosis, Actinic

NCT00847912 2021-06-11

VAKCCT

Phase 4 Completed

954 enrolled 11 charts

Dermatologic

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Neoplasms, Neoplasms by Site, Skin Diseases, Skin Neoplasms, Neoplasms, Basal Cell, Neoplasms, Squamous Cell

NCT03996252 2020-12-07

Combination Topical Therapy for Treatment of Scalp Actinic Keratoses

Phase EARLY_PHASE1 Terminated

15 enrolled

Dermatologic

Keratosis, Actinic

NCT03727074 2020-03-18

Bioequivalence Study to Compare Sol-Gel Technologies' 5-FU Cream With Efudex® (5-FU) Cream

Phase 3 Completed

462 enrolled

Dermatologic

Keratosis, Actinic

NCT02705352 2020-03-09

5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts

Phase 2 Completed

1 enrolled 7 charts

Dermatologic

Ectropion, Skin Neoplasms

NCT02362152 2019-12-13

RAPID-ACT

Completed

1,168 enrolled

Dermatologic

Keratosis, Actinic

NCT02616601 2019-07-17

Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis

Phase 3 Completed

422 enrolled 10 charts

Dermatologic

Keratosis, Actinic

NCT00696488 2018-09-10

Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population

Phase 4 Completed

20 enrolled 4 charts

Dermatologic

Keratosis, Actinic

NCT00814528 2018-09-10

Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses

Phase NA Withdrawn

Dermatologic

Keratosis, Actinic

NCT02550678 2018-06-06

ASN-002-001

Phase 1/2 Completed

16 enrolled

Dermatologic

Basal Cell Nevus Syndrome, Skin Neoplasms

NCT02281682 2017-10-30

Akti

Phase 4 Unknown

624 enrolled

Dermatologic

Keratosis, Actinic

NCT01183663 2016-06-03

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

Phase 1 Completed

180 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryOther hematologic neoplasmPlasma cell

Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT02019355 2016-05-19

AK

Phase EARLY_PHASE1 Completed

132 enrolled

Dermatologic

Keratosis, Actinic

NCT00121511 2015-05-27

The Effect of Efudex Treatment on Photoaged Skin

Phase NA Completed

21 enrolled

Dermatologic

Keratosis, Keratosis, Actinic

NCT01354717 2014-10-20

Bioequivalence Study of Generic Fluorouracil 0.5% Cream and 0.5% Carac® and Placebo

Phase 3 Completed

377 enrolled

Dermatologic

Keratosis, Actinic

NCT02242747 2014-09-17

Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis

Phase NA Completed

100 enrolled

Dermatologic

Keratosis, Actinic

NCT00003549 2012-10-08

S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer

Phase 2 Completed

80 enrolled

Dermatologic

Carcinoma, Merkel Cell

NCT00019513 2012-03-23

Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas

Phase 1 Completed

108 enrolled

DermatologicGastrointestinalLymphoidOther hematologic neoplasmThoracic

Bile Duct Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Hodgkin Disease, Liver Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Pancreatic Neoplasms, Sezary Syndrome, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Small Cell Lung Carcinoma

Clinical Trials

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

PANGEA

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Actinic Keratoses Treated With 5-fluorouracil Plus Aluminum

Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis

Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

CALM

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

QUILT-3.045: NANT Merkel Cell Carcinoma (MCC) Vaccine: Combination Immunotherapy in Subjects With MCC Who Have Progressed on or After PD-L1 Therapy

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Carac & PDT Combination in the Treatment Of Actinic Keratoses

MODULATE

Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic Keratoses

The Efficacy and Safety of Using Intralesional 5-fluorouracil for Basal Cell Carcinoma

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

PACKS

Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinoma

Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

VAKCCT

Combination Topical Therapy for Treatment of Scalp Actinic Keratoses

Bioequivalence Study to Compare Sol-Gel Technologies' 5-FU Cream With Efudex® (5-FU) Cream

5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts

RAPID-ACT

Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis

Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population

Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses

ASN-002-001

Akti

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

AK

The Effect of Efudex Treatment on Photoaged Skin

Bioequivalence Study of Generic Fluorouracil 0.5% Cream and 0.5% Carac® and Placebo

Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis

S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer

Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas