Announcements Trials
Browse Landscape

Phase

Phase 2 11Phase 1 9Phase NA 6Phase 3 5Phase 1/2 4Phase 2/3 1

Status

Completed 4Active not recruiting 1

Sponsor Class

INDUSTRY 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 45Lymphoid 15Other hematologic neoplasm 11CNS 10Myeloid 5Dermatologic 5Sarcoma 2Other solid neoplasm 1Other neoplasm 1Gynecologic 1Gastrointestinal 1Breast 1

Conditions

Uveal Melanoma 3Melanoma 3Neoplasm Metastasis 1

Interventions

Dacarbazine 27Nivolumab 26pembrolizumab 22Ipilimumab 203-ingenyl angelate 11Interferon-alpha 10Imiquimod 10Temozolomide 9trametinib 8Vemurafenib 8Photochemotherapy 8Aminolevulinic Acid 8methyl 5-aminolevulinate 7dabrafenib 7cemiplimab 7aldesleukin 7Introns 7Surgical Procedures, Operative 6Radiotherapy 6Interferon alpha-2 6Fluorouracil 6Paclitaxel 5Melphalan 5Interleukin-2 5Cisplatin 5Chemotherapy, Adjuvant 5talimogene laherparepvec 4binimetinib 4Specimen Handling 4Opdualag 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 3 × Melphalan × Dermatologic × Clear all
NCT02678572 2023-12-21

FOCUS

Delcath Systems Inc.

Phase 3 Completed
102 enrolled 1 FDA
Dermatologic

Uveal Melanoma

NCT05022901 2023-12-21

An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma

Delcath Systems Inc.

Phase 3 Active not recruiting
30 enrolled
Dermatologic

Uveal Melanoma

NCT00324727 2021-06-21

Hepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to Melanoma

Delcath Systems Inc.

Phase 3 Completed
93 enrolled
Dermatologic

Uveal Melanoma, Melanoma, Neoplasm Metastasis

NCT00003789 2013-07-16

Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg

National Cancer Institute (NCI)

Phase 3 Completed
216 enrolled
Dermatologic

Melanoma

NCT00001296 2008-03-04

A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma

National Institutes of Health Clinical Center (CC)

Phase 3 Completed
122 enrolled
Dermatologic

Melanoma

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