Clinical Trials Browser

INDUSTRY × Temozolomide × Dermatologic × Clear all

Melanoma, Cutaneous Malignant

NCT07492680 2026-03-25

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Phase 2 Not yet recruiting

260 enrolled

CNSDermatologicGastrointestinal

Brain Neoplasms, Melanoma, Pancreatic Neoplasms

NCT07310784 2026-03-03

A Phase II Trial of LM103 in Advanced Melanoma

Phase 2 Recruiting

92 enrolled

Dermatologic

Advanced Melanoma

NCT06346067 2026-02-27

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

Phase 3 Active not recruiting

78 enrolled

Dermatologic

Melanoma

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

Phase 1/2 Active not recruiting

125 enrolled

BreastCNSDermatologicGenitourinary

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT06703398 2025-12-23

MIZAR-003

Phase 2 Recruiting

98 enrolled

Dermatologic

Melanoma

NCT06624644 2025-09-10

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

Phase 2/3 Recruiting

135 enrolled

Dermatologic

Melanoma

NCT05647954 2022-12-13

A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver

Phase 3 Unknown

350 enrolled

DermatologicEndocrineNET

Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms

NCT02288897 2022-01-19

PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma

Phase 3 Terminated

20 enrolled 13 charts

Dermatologic

Melanoma, Recurrence

NCT01704287 2020-05-18

KEYNOTE 002

Phase 2 Completed

540 enrolled 20 charts

Dermatologic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Melanoma

NCT00804908 2018-06-06

A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma

Phase 2 Completed

346 enrolled 15 charts

Dermatologic

Melanoma, Skin Neoplasms

NCT00526617 2017-11-21

A Phase I Study of ABT-888 in Combination With Temozolomide in Cancer Patients

Phase 1 Completed

41 enrolled

BreastDermatologicGastrointestinalGynecologic

Breast Neoplasms, Fallopian Tube Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms

NCT00091572 2017-06-06

Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)

Phase 3 Completed

859 enrolled 11 charts

Dermatologic

Melanoma

NCT00831545 2017-05-09

Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064)

Phase 2 Completed

162 enrolled

BreastDermatologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT00724841 2016-07-22

A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma

Phase 1/2 Terminated

1 enrolled

Dermatologic

Melanoma

NCT00338130 2014-08-13

Randomised Study to Compare the Efficacy of AZD6244 vs TMZ

Phase 2 Completed

239 enrolled

Dermatologic

Melanoma

NCT00395070 2013-09-13

A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma

Phase 3 Completed

390 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT01294735 2012-08-15

Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)

Phase 1 Completed

19 enrolled

CNSDermatologic

Glioblastoma, Melanoma

NCT00257205 2012-07-02

CP-675,206 Versus Either Dacarbazine Or Temozolomide In Patients Without Prior Therapy

Phase 3 Completed

655 enrolled

Dermatologic

Melanoma

NCT00409383 2011-11-07

Abraxane and Temodar Plus Genasense in Advanced Melanoma

Phase 1 Unknown

28 enrolled

Dermatologic

Melanoma

NCT00609011 2010-08-23

Phase 1 Study of MPC-6827 and Temozolomide in Metastatic Melanoma

Phase 1/2 Completed

22 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT00991250 2010-02-05

SentoClone® Compared to Reference Treatment in Advanced Malignant Melanoma

Phase 2 Unknown

140 enrolled

Dermatologic

Melanoma

NCT00272415 2009-03-11

A Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics in Patients With Melanoma

Phase 1 Terminated

39 enrolled

Dermatologic

Deafness, Autosomal Recessive 53, Melanoma

NCT00383851 2007-12-06

Randomized Trial of ATN-224 and Temozolomide in Advanced Melanoma

Phase 2 Unknown

60 enrolled

Dermatologic

Melanoma

Clinical Trials

SUPRAME

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

A Phase II Trial of LM103 in Advanced Melanoma

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

MIZAR-003

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver

PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma

KEYNOTE 002

A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma

A Phase I Study of ABT-888 in Combination With Temozolomide in Cancer Patients

Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)

Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064)

A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma

Randomised Study to Compare the Efficacy of AZD6244 vs TMZ

A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma

Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)

CP-675,206 Versus Either Dacarbazine Or Temozolomide In Patients Without Prior Therapy

Abraxane and Temodar Plus Genasense in Advanced Melanoma

Phase 1 Study of MPC-6827 and Temozolomide in Metastatic Melanoma

SentoClone® Compared to Reference Treatment in Advanced Malignant Melanoma

A Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics in Patients With Melanoma

Randomized Trial of ATN-224 and Temozolomide in Advanced Melanoma