Announcements Trials
Browse Landscape

Phase

Phase 2 22Phase 1 9Phase 1/2 7Phase 3 4Phase EARLY_PHASE1 2Phase 4 1

Status

Terminated 3Completed 2Unknown 1Recruiting 1

Sponsor Class

INDUSTRY 4OTHER 3

Study Type

Interventional 7

Sponsor

Cancer Type

Dermatologic 7Gastrointestinal 6Thoracic 3Sarcoma 2Other solid neoplasm 2Breast 2CNS 1

Conditions

Melanoma 7Uveal Melanoma 2Neoplasm Metastasis 1Colorectal Neoplasms 1

Interventions

pembrolizumab 81Nivolumab 55Ipilimumab 44Cyclophosphamide 37aldesleukin 26Interleukin-2 25Temozolomide 17fludarabine 16fludarabine phosphate 15trametinib 11dabrafenib 11Radiotherapy 11Biopsy 11avelumab 10Paclitaxel 9spartalizumab 8cemiplimab 8Dacarbazine 8Cisplatin 8Bevacizumab 8sargramostim 7binimetinib 7Fluorouracil 7poly ICLC 6lenvatinib 6epacadostat 6atezolizumab 6Magnetic Resonance Spectroscopy 6Granulocyte-Macrophage Colony-Stimulating Factor 6montanide ISA 51 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 1/2 × binimetinib × Dermatologic × Clear all
NCT03947385 2026-01-27

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

IDEAYA Biosciences

Phase 1/2 Recruiting
336 enrolled
DermatologicGastrointestinal

Uveal Melanoma, Melanoma, Colorectal Neoplasms

NCT05340621 2025-03-07

NAUTILUS: OKI-179 Plus Binimetinib in Patients with Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)

OnKure, Inc.

Phase 1/2 Completed
36 enrolled
Dermatologic

Melanoma

NCT04655157 2024-05-23

QUAD01

University of Pittsburgh

Phase 1/2 Terminated
2 enrolled 12 charts
Dermatologic

Melanoma

NCT04720768 2024-01-05

CELEBRATE

Peter MacCallum Cancer Centre, Australia

Phase 1/2 Unknown
78 enrolled
Dermatologic

Melanoma, Neoplasm Metastasis

NCT02902042 2021-02-16

IMMU-TARGET

University Hospital, Essen

Phase 1/2 Completed
16 enrolled
Dermatologic

Melanoma

NCT01562899 2020-12-10

A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors

Pfizer

Phase 1/2 Terminated
77 enrolled
Dermatologic

Melanoma

NCT01801358 2020-09-16

A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma

Array BioPharma

Phase 1/2 Terminated
38 enrolled 31 charts
Dermatologic

Uveal Melanoma, Melanoma

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