Announcements Trials
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Phase

Phase 2 2Phase 1 2

Status

Completed 17Terminated 9Active not recruiting 4Recruiting 2Withdrawn 1Unknown 1Suspended 1

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Dermatologic 4Thoracic 3Gynecologic 2Gastrointestinal 2CNS 2Tumor-Agnostic 1Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1Head & Neck 1Endocrine 1Breast 1

Conditions

Melanoma 4Skin Neoplasms 1Brain Neoplasms 1

Interventions

pembrolizumab 70Nivolumab 47Ipilimumab 27Specimen Handling 15Magnetic Resonance Spectroscopy 15trametinib 14Biopsy 13dabrafenib 11cemiplimab 11avelumab 11Cyclophosphamide 11binimetinib 10Radiotherapy 9CTLA-4 Antigen 9fludarabine 8encorafenib 7atezolizumab 7Radiosurgery 7Immunoglobulin G 7Disulfides 7Cisplatin 7fludarabine phosphate 6durvalumab 6tislelizumab 5relatlimab 5lenvatinib 5dostarlimab 5Pemetrexed 5Paclitaxel 5Introns 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Active not recruiting × cobimetinib × Dermatologic × Clear all
NCT03175432 2026-04-15

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
29 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT04835805 2026-03-30

A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma.

Genentech, Inc.

Phase 1 Active not recruiting
65 enrolled
Dermatologic

Melanoma

NCT02721459 2026-03-02

XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Active not recruiting
26 enrolled
Dermatologic

Melanoma, Skin Neoplasms

NCT04722575 2025-03-13

NEO-TIM

Fondazione Melanoma Onlus

Phase 2 Active not recruiting
95 enrolled
Dermatologic

Melanoma

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