Clinical Trials Browser

Interventional × sonidegib × Dermatologic × Clear all

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT03534947 2025-12-16

SONIB

Phase 2 Completed

16 enrolled

Dermatologic

Carcinoma, Basal Cell, Skin Neoplasms

NCT04679480 2024-07-30

Anti-PD1-antibody and Pulsed HHI for Advanced BCC

Phase 2 Active not recruiting

20 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT00880308 2020-12-19

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

Phase 1 Completed

103 enrolled

CNSDermatologic

Carcinoma, Basal Cell, Medulloblastoma

NCT01208831 2020-12-19

An East Asian Study of LDE225

Phase 1 Completed

45 enrolled

CNSDermatologic

Carcinoma, Basal Cell, Medulloblastoma

NCT01327053 2019-08-28

BOLT

Phase 2 Completed

230 enrolled 26 charts

Dermatologic

Carcinoma, Basal Cell, Skin Neoplasms

NCT02303041 2019-01-29

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Phase 2 Terminated

10 enrolled 11 charts

Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell, Skin Neoplasms

NCT01529450 2017-01-16

Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors

Phase NA Completed

11 enrolled 10 charts

Dermatologic

Carcinoma, Basal Cell

NCT02002689 2016-05-02

SIGNATURE

Phase 2 Terminated

10 enrolled 9 charts

DermatologicGastrointestinalGynecologicOther hematologic neoplasm

Basal Cell Nevus Syndrome, Colonic Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT01350115 2015-10-19

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Phase 2 Completed

10 enrolled 9 charts

Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

Clinical Trials

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

SONIB

Anti-PD1-antibody and Pulsed HHI for Advanced BCC

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

An East Asian Study of LDE225

BOLT

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors

SIGNATURE

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)