Clinical Trials

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

71 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Melanoma, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06307093 2024-03-12

Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms

DermatologicHead & NeckThoracic

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Lung Neoplasms, Melanoma, Neoplasms

NCT04544748 2024-03-06

A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies

DermatologicGenitourinaryThoracic

48 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Histologic Type, Urologic Neoplasms

NCT04137900 2024-02-05

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

DermatologicLymphoidThoracic

499 enrolled

Carcinoma, Non-Small-Cell Lung, Lymphoma, Melanoma, Neoplasm Metastasis

NCT06239623 2024-02-02

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

60 enrolled

Melanoma

NCT03068624 2024-01-25

Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

34 enrolled

Uveal Melanoma

NCT05781386 2023-09-21

A Phase I Trial of SIM1811-03 in Subjects With Advanced Tumors

255 enrolled

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT05739006 2023-08-02

Clinical Trial to Evaluate the PK and Safety of BCD-201 and Keytruda® in Patients With Advanced Malignancies

131 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05798533 2023-07-10

Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)

6 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05928962 2023-07-10

An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomas

Melanoma

NCT04763083 2023-07-07

First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies

DermatologicLymphoidOther hematologic neoplasmThoracic

90 enrolled

Carcinoma, Non-Small-Cell Lung, Lymphoma, Follicular, Melanoma, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT05451407 2023-07-07

Efficacy and Safety of TQB2618 Injection Combined With Toripalimab Injection in Patients With Advanced Melanoma

50 enrolled

Melanoma

NCT03803397 2023-07-06

Arm 1: Lysate Pulsed Dendritic Cells (PV-001-DC) in Patients With Melanoma

Melanoma

NCT03982212 2023-05-19

A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT05539157 2023-04-04

Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors

1 enrolled

Neoplasms, Skin Neoplasms

NCT05798546 2023-04-04

Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)

21 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03775525 2022-12-23

GEN602

BreastDermatologicGastrointestinalHead & NeckLymphoidSarcoma

127 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Basal Cell, Colonic Neoplasms, Lymphoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT00986661 2022-11-02

A Study to Assess PV-10 Chemoablation of Cancer of the Liver

BreastDermatologicEndocrineGastrointestinalThoracic

78 enrolled

Uveal Melanoma, Breast Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04118868 2022-10-12

Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.

DermatologicLymphoid

Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous

NCT05569057 2022-10-07

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

100 enrolled

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT01946373 2022-10-04

T Cell Transfer With or Without Dendritic Cell Vaccination in Patients With Melanoma

20 enrolled

Melanoma

NCT03634982 2022-09-01

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

133 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Noonan Syndrome, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT03934827 2022-08-11

MICROBIOME

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

120 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Urethral Neoplasms, Uterine Neoplasms

NCT03385486 2022-05-03

Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors

72 enrolled

Melanoma

NCT02437279 2022-04-15

OpACIN

20 enrolled

Melanoma

NCT02637531 2022-04-04

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

BreastDermatologicEndocrineOther solid neoplasmThoracic

219 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Adrenocortical Carcinoma, Triple Negative Breast Neoplasms

NCT05235607 2022-02-11

Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors

DermatologicGastrointestinalGenitourinary

60 enrolled

Urinary Bladder Neoplasms, Carcinoma, Melanoma, Colorectal Neoplasms

NCT05190185 2022-01-13

A Clinical Trial of TAA06 Injection in Advanced Solid Tumors

DermatologicGastrointestinalThoracic

18 enrolled

Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT05103891 2021-12-01

Relative Bioavailability of Binimetinib 3 x 15 mg and 45 mg Formulations

14 enrolled

Melanoma

NCT03291002 2021-11-04

Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC

98 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Adenoid Cystic, Melanoma

NCT05070221 2021-10-07

Study of Oncolytic Virus in Combination With HX-008 and Axitinib in Melanoma Patients With Liver Metastasis

Melanoma

NCT05068453 2021-10-05

Study of Oncolytic Virus in Combination With HX-008 and Radiotherapy in Melanoma Patients With Liver Metastasis

15 enrolled

Melanoma

NCT04773951 2021-08-24

A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors

DermatologicGenitourinary

156 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma

NCT04142931 2021-03-24

Sequentional Immuno Apheresis Plasma Volume Escalation Cohort Study of Reduction of Soluble Tumor Necrosis Factor Receptors 1 and 2 (sTNFR1/2) With or Without Nivolumab in Patients With Inoperable or Metastatic Solid Tumors

BreastDermatologicGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Triple Negative Breast Neoplasms

NCT04756934 2021-02-16

A Study of HX008 Plus LP002 for the Treatment of Patients With Advanced Melanoma

63 enrolled

Melanoma

NCT04197882 2021-02-10

Clinical Study to Evaluate OrienX010 in Combination With Toripalimab as Neoadjuvant Treatment in Advanced Melanoma

33 enrolled

Melanoma

NCT03747744 2020-12-29

myDCTV

18 enrolled

Melanoma

NCT03088176 2020-10-12

Combining Talimogene Laherparepvec With BRAF and MEK Inhibitors in BRAF Mutated Advanced Melanoma

4 enrolled

Melanoma

NCT03086174 2020-09-30

Tolerability and Pharmacokinetics of Toripalimab in Combination With Axitinib in Patients With Kidney Cancer and Melanoma

DermatologicGenitourinary

24 enrolled

Kidney Neoplasms, Melanoma

NCT03734913 2020-07-22

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors

CNSDermatologicEndocrineNETThoracic

65 enrolled

Carcinoma, Basal Cell, Glioblastoma, Medulloblastoma, Neuroendocrine Tumors, Small Cell Lung Carcinoma

NCT04072900 2020-04-28

A Personalized NeoAntigen Cancer Vaccine Combined With Anti-PD-1 in Melanoma

Melanoma, Neoplasm Metastasis

NCT04357509 2020-04-24

The Tolerance,Pharmacokinetic Characteristics,Safety and Efficacy of ScTIL210 in the Treatment of Melanoma

32 enrolled

Melanoma

NCT04206358 2019-12-20

Study to Evaluate OrienX010 in Combination With JS001 in the Treatment of Stage IV (M1c) Liver Metastasis From Melanoma

Melanoma

NCT04138342 2019-10-24

Topical Fluorescent Nanoparticles Conjugated Somatostatin Analog for Suppression and Bioimaging Breast Cancer

BreastDermatologic

Breast Neoplasms, Skin Diseases, Skin Neoplasms

NCT03903458 2019-04-08

ENIgMA

21 enrolled

Melanoma

NCT03353402 2019-04-03

Fecal Microbiota Transplantation (FMT) in Metastatic Melanoma Patients Who Failed Immunotherapy

40 enrolled

Melanoma

NCT02366546 2018-10-24

Investigator Initiated Phase 1 Study of TBI-1301

DermatologicGastrointestinalGynecologicHead & NeckSarcoma

9 enrolled

Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT03050047 2018-08-31

A Multicenter Open-Label Single-Arm Multi-Cohort Phase I Study of BCD-100 in Patients With Advanced Solid Tumors