Clinical Trials

252 enrolled

BreastDermatologic

Melanoma, Inflammatory Breast Neoplasms

NCT06279143 2026-05-26

dOCT-pBCC

Completed

210 enrolled

DermatologicGenitourinary

Carcinoma, Carcinoma, Basal Cell, Eyelid Diseases, Eyelid Neoplasms, Hypersensitivity, Neoplasms, Glandular and Epithelial, Recurrence, Skin Diseases, Skin Neoplasms

NCT06391099 2026-05-26

Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer

Phase NA Suspended

60 enrolled

Carcinoma, Renal Cell, Melanoma

NCT07606287 2026-05-26

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

Phase NA Not yet recruiting

4,000 enrolled

BreastCNSDermatologicGastrointestinalHead & Neck

Breast Neoplasms, Endocrine Gland Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Skin Neoplasms, Soft Tissue Neoplasms, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT03210935 2026-05-22

CARADERM

9,000 enrolled

Phase NA Active not recruiting

Carcinoma, Merkel Cell

NCT03336606 2026-05-22

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Phase 1 Completed

13 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT04611568 2026-05-22

War on Melanoma™ Public Health & Education Campaign

75,000 enrolled

Melanoma

NCT05053555 2026-05-22

High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies

DermatologicGastrointestinal

60 enrolled

Carcinoma, Hepatocellular, Melanoma, Pancreatic Neoplasms

NCT05225428 2026-05-22

VERDI

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

1,020 enrolled

Breast Neoplasms, Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT05498792 2026-05-22

Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma

Phase EARLY_PHASE1 Recruiting

12 enrolled

Melanoma

NCT06489301 2026-05-22

Mechanisms for Laser-Induced Rejuvenation

12 enrolled

Phase 3 Not yet recruiting

Skin Neoplasms

NCT07273656 2026-05-22

TIRBACRYO

59 enrolled

Keratosis, Keratosis, Actinic

NCT07330323 2026-05-22

CARES

150 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Skin Neoplasms

NCT07405086 2026-05-22

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Phase 4 Recruiting

160 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT02479698 2026-05-20

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

100 enrolled

Acquired Immunodeficiency Syndrome, Neoplasms, Carcinoma, Merkel Cell, Encephalitis, Viral

NCT03093909 2026-05-20

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

DermatologicGenitourinarySarcoma

44 enrolled

Bone Neoplasms, Melanoma, Osteosarcoma, Urologic Neoplasms

NCT04253080 2026-05-20

ENZYMELA

Phase NA Completed

127 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Diabetes Mellitus, Insulin-Dependent, 12, Melanoma

NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Phase 3 Terminated

19 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT04751396 2026-05-20

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

125 enrolled

Phase 1 Active not recruiting

Arthritis, Rheumatoid, Autoimmune Diseases, Colitis, Ulcerative, Crohn Disease, Lupus Erythematosus, Systemic, Melanoma, Psoriasis, Spondylitis, Ankylosing, Inflammatory Bowel Diseases, Arthritis, Psoriatic, Arthritis, Reactive

NCT04875728 2026-05-20

The Impact of an Antibiotic (Cefazolin) Before Surgery on the Microbiome in Patients With Stage I-II Melanoma

20 enrolled

Clinical Stage I Cutaneous Melanoma AJCC v8

NCT05978141 2026-05-20

A Registry for People With T-cell Lymphoma

DermatologicLymphoidOther hematologic neoplasm

1,000 enrolled

Subcutaneous panniculitis-like T-cell lymphoma, Immunoblastic Lymphadenopathy, Mycosis Fungoides, Sezary Syndrome, Leukemia, Prolymphocytic, T-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Leukemia, Large Granular Lymphocytic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Lymphoma, Primary Cutaneous Anaplastic Large Cell, Enteropathy-Associated T-Cell Lymphoma

NCT06814496 2026-05-20

RABBIT

Phase 1/2 Recruiting

30 enrolled

CNSDermatologicGenitourinaryGynecologicThoracic

Sinonasal undifferentiated carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Glioblastoma, Melanoma, Testicular Neoplasms, Carcinoma, Merkel Cell, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory

NCT03610022 2026-05-19

OPTIVISMO-1

Phase 4 Completed

27 enrolled

Carcinoma, Basal Cell

NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

CNSDermatologicGastrointestinalGenitourinarySarcoma

48 enrolled

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT05779423 2026-05-19

Cryoablation+Ipilimumab+Nivolumab in Melanoma

37 enrolled

Phase 2 Not yet recruiting

Melanoma, Skin Neoplasms

NCT07340619 2026-05-19

EPIBREAST

51 enrolled

Phase 2/3 Not yet recruiting

Melanoma, Neoplasm Metastasis

NCT07597070 2026-05-19

UNIFIER

1,200 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05034536 2026-05-18

PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma

Phase 2 Active not recruiting

36 enrolled

Melanoma

NCT06365619 2026-05-18

NeoRelapse

25 enrolled

Melanoma

NCT06712927 2026-05-18

Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases

60 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT07102212 2026-05-18

FOCUS

BreastDermatologicGenitourinaryPlasma cellThoracic

120 enrolled

Alzheimer Disease, Anxiety Disorders, Breast Neoplasms, Depression, Fatigue, Lung Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Prostatic Neoplasms

NCT07285044 2026-05-18

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT05574101 2026-05-15

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

Phase 2 Active not recruiting

34 enrolled

Carcinoma, Squamous Cell, Skin Neoplasms

NCT05704647 2026-05-15

Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases

30 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Melanoma

NCT06043947 2026-05-15

SURVIMON

Active not recruiting

100,000 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms

NCT06889766 2026-05-15

LauT1

9 enrolled

DermatologicSarcoma

Melanoma, Sarcoma

NCT05715255 2026-05-14

Adaptive Symptom Self-Management Immunotherapy Study

BreastDermatologicGastrointestinalThoracic

400 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Rectal Neoplasms, Skin Neoplasms

NCT07586891 2026-05-14

Exploratory Study With Parallel Controls on the Safety and Efficacy of Neoadjuvant Low Branched-Chain Amino Acid Diet in Combination With Anti-PD-1 Monoclonal Antibody for Stage III Melanoma

80 enrolled

Phase EARLY_PHASE1 Recruiting

Melanoma

NCT07586904 2026-05-14

Efficacy and Safety of Neoadjuvant Cadonilimab Plus High-Dose Recombinant Human Interferon α1b in Stage III/IV Melanoma.

10 enrolled

Phase 4 Not yet recruiting

Melanoma

NCT07587749 2026-05-14

Skin Subs vs Secondary Intention

50 enrolled

Phase 2 Active not recruiting

Skin Substitutes

NCT03420508 2026-05-13

Treating Patients With Melanoma and ALK Alterations With Ensartinib

18 enrolled

Melanoma

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT07584291 2026-05-13

Liquid Biopsy Multi-Omics and Biomarker Development in Melanoma

200 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Melanoma

NCT01624220 2026-05-12

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

Phase NA Completed

41 enrolled 8 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Prostatic Neoplasms, Sarcoma, Spinal Cord Neoplasms, Thyroid Neoplasms

NCT02437227 2026-05-12

PanRAF

Phase 1 Completed

31 enrolled 16 charts