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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 57Other hematologic neoplasm 39Dermatologic 4Sarcoma 3Plasma cell 3Myeloid 3CNS 3Gynecologic 2Genitourinary 2Breast 2Endocrine 1

Conditions

Pituitary Neoplasms 2Spinal Cord Neoplasms 1Rhabdoid Tumor 1Recurrence 1Prolactinoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pituitary Diseases 1Optic Nerve Glioma 1Oligodendroglioma 1Neuroendocrine Tumors 1Medulloblastoma 1Lymphoma, Large-Cell, Anaplastic 1Leukemia, Large Granular Lymphocytic 1Familial ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Colorectal Neoplasms 1Cirrhosis, Familial, with Pulmonary Hypertension 1Choroid Plexus Neoplasms 1Cholangiocarcinoma 1Burkitt Lymphoma 1Bile Duct Neoplasms 1Astrocytoma 1Adrenocortical Carcinoma 1Adrenal Gland Neoplasms 1Adrenal Cortex Neoplasms 1Adenoma, Chromophobe 1Adenoma, Basophil 1Adenoma, Acidophil 1

Interventions

entinostat 1Ritonavir 1Radiotherapy 1Indinavir 1Fentanyl 1Dexamethasone 1Calcium Dobesilate 190Y-octreotide, DOTA-Tyr(3)- 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Burkitt Lymphoma × Dexamethasone × Endocrine × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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