Clinical Trials Browser

Interventional × Cushing Syndrome × Endocrine × Clear all

Cushing Syndrome, Hyperaldosteronism, Adrenocortical Adenoma

NCT03604198 2026-04-21

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT07412782 2026-02-17

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

Phase NA Recruiting

100 enrolled

EndocrineOther

Bone Diseases, Metabolic, Cushing Syndrome, Dwarfism, Pituitary, Neoplasms, Obesity, Osteogenesis Imperfecta, Osteoporosis, Malnutrition, Overweight

NCT05307328 2025-10-08

RESCUE

Phase 2 Completed

26 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT03697109 2025-07-16

GRACE

Phase 3 Completed

152 enrolled 28 charts

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Pituitary ACTH Hypersecretion

NCT05804669 2025-04-10

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Phase 1/2 Recruiting

18 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT04373265 2024-02-23

Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)

Phase 1 Completed

15 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Adrenal Gland Diseases, Adrenocortical Hyperfunction, Cushing Syndrome, Diabetes Mellitus, Type 2, Endocrine System Diseases, Hyperglycemia, Hypertension, Pathologic Processes, Glucose Intolerance, Adrenocortical Carcinoma

NCT02804750 2019-10-15

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Phase 2 Completed

35 enrolled 13 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT02001051 2018-06-14

Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism

Phase 2 Terminated

4 enrolled 10 charts

EndocrineOther

Adrenal incidentaloma, Adrenal Gland Neoplasms, Cushing Syndrome, Diabetes Mellitus, Hypercholesterolemia, Hypertension, Obesity, Osteoporosis

NCT01676025 2017-10-06

PRA

Phase NA Completed

83 enrolled

Endocrine

Adrenal incidentaloma, Adrenal Gland Diseases, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma

NCT03145285 2017-05-10

ABACUS

Phase 2 Unknown

10 enrolled

Endocrine

Cushing Syndrome, Adrenocortical Carcinoma

NCT02618694 2017-03-03

PostLapAdrnl

Phase NA Completed

13 enrolled

Endocrine

Adrenal Gland Diseases, Cushing Syndrome, Pheochromocytoma

NCT00936741 2014-04-02

An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome

Phase 3 Completed

30 enrolled 8 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Choristoma, Cushing Syndrome, Hirsutism, Pituitary Diseases, Pituitary ACTH Hypersecretion

NCT01371565 2014-03-18

Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome

Phase 3 Completed

4 enrolled 7 charts

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary Diseases, Pituitary ACTH Hypersecretion

NCT01959711 2013-10-10

Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy

Phase 4 Completed

65 enrolled

Endocrine

Adrenal Gland Neoplasms, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma

NCT00569582 2013-08-22

SEISMIC

Phase 3 Completed

50 enrolled 8 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Choristoma, Cushing Syndrome, Hirsutism, Pituitary Diseases, Pituitary ACTH Hypersecretion

Clinical Trials

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

RESCUE

GRACE

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism

PRA

ABACUS

PostLapAdrnl

An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome

Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome

Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy

SEISMIC