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Phase

Phase NA 18Phase 2 12Phase 1 6Phase 3 4Phase EARLY_PHASE1 3Phase 4 3Phase 2/3 1Phase 1/2 1

Status

Completed 8Recruiting 5Unknown 3Active not recruiting 3Terminated 2Not yet recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 30Other hematologic neoplasm 10Thoracic 9Breast 7Genitourinary 6Lymphoid 5Head & Neck 5Gynecologic 5CNS 4Tumor-Agnostic 3Plasma cell 3Myeloid 2Sarcoma 1Other neoplasm 1Endocrine 1Dermatologic 1

Conditions

Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Ovarian Neoplasms 1Neoplasms by Site 1Neoplasms by Histologic Type 1Neoplasms 1Multiple Myeloma 1Lymphoproliferative Disorders 1Laryngeal Neoplasms 1Histiocytosis, Langerhans-Cell 1Hematologic Neoplasms 1Glioma 1Gastrointestinal Neoplasms 1Erdheim-Chester Disease 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2/3 × Not yet recruiting × Endocrine × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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