Clinical Trials

32 enrolled

Adenomatous Polyposis Coli

NCT05223036 2026-05-14

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Phase 2 Terminated

15 enrolled

Attenuated familial adenomatous polyposis, Duodenal Neoplasms, Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT05630794 2026-05-13

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

Phase 1 Recruiting

36 enrolled

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT06557733 2026-05-13

An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

Phase 2 Recruiting

38 enrolled

Phase 2 Not yet recruiting

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT06308445 2026-05-08

RAPA-4-PAF

25 enrolled

Phase NA Enrolling by invitation

Adenomatous Polyposis Coli

NCT06649825 2026-04-24

VitB1; FAP

Adenomatous Polyposis Coli

NCT05552755 2026-04-16

TUPELO

Phase 1/2 Recruiting

67 enrolled

Adenomatous Polyposis Coli

NCT07463599 2026-03-11

Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

Phase 1/2 Recruiting

126 enrolled

Phase NA Not yet recruiting

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT06881303 2025-11-18

RESTODIG

100 enrolled

Colitis, Ulcerative, Crohn Disease, Gastrointestinal Neoplasms, Adenomatous Polyposis Coli

NCT06578637 2025-09-04

BHB-FAP

20 enrolled

Adenomatous Polyposis Coli, Polyps

NCT07066046 2025-07-16

Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions

1,000 enrolled

Adenoma, Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT06538402 2025-07-09

TESTIMONY

120 enrolled

Phase NA Active not recruiting

Colitis, Ulcerative, Adenomatous Polyposis Coli

NCT03847636 2025-03-11

C2D2

44 enrolled

Adenomatous Polyposis Coli

NCT03649971 2025-02-03

A Study of Guselkumab in Participants With Familial Adenomatous Polyposis

77 enrolled

Phase 2 Active not recruiting

Adenomatous Polyposis Coli

NCT04230499 2025-01-09

Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

30 enrolled

Adenomatous Polyposis Coli

NCT03095703 2024-10-24

Sirolimus and Familial Adenomatous Polyposis (FAP)

4 enrolled 10 charts

Adenomatous Polyposis Coli

NCT05402891 2024-10-04

Lithium in FAP

12 enrolled

Adenomatous Polyposis Coli

NCT06545526 2024-08-09

Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis

Phase 3 Recruiting

28 enrolled

Adenomatous Polyposis Coli

NCT06435533 2024-05-30

coldAPC

Adenomatous Polyposis Coli

NCT03806426 2024-04-25

Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis

Phase 3 Unknown

204 enrolled

Adenomatous Polyposis Coli, Polyps

NCT02113202 2023-10-27

FLUOFAP

17 enrolled

Adenomatous Polyposis Coli

NCT05687318 2023-09-06

A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment

337 enrolled

Adenomatous Polyposis Coli

NCT05014360 2023-06-02

A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis

42 enrolled

Adenomatous Polyposis Coli

NCT00503035 2023-02-13

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

51 enrolled 10 charts

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT02961374 2022-07-26

Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer

46 enrolled 13 charts

Attenuated familial adenomatous polyposis, Adenomatous Polyposis Coli

NCT01725490 2021-09-20

The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study

34 enrolled

Adenomatous Polyposis Coli

NCT01483144 2021-06-08

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

Phase 3 Completed

171 enrolled 13 charts

Adenomatous Polyposis Coli

NCT00525655 2021-03-23

Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)

31 enrolled

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT00585312 2021-02-21

CHIP

Phase 3 Terminated

106 enrolled 10 charts

Adenomatous Polyposis Coli

NCT04695184 2021-01-15

Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

50 enrolled

Colitis, Ulcerative, Crohn Disease, Adenomatous Polyposis Coli, Colorectal Neoplasms, Pouchitis, Anastomotic Leak

NCT04695964 2021-01-15

Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

50 enrolled

Colitis, Ulcerative, Crohn Disease, Adenomatous Polyposis Coli, Colorectal Neoplasms, Pouchitis, Anastomotic Leak

NCT04709445 2021-01-14

Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses

100 enrolled

Colitis, Ulcerative, Crohn Disease, Diverticulitis, Gastrointestinal Neoplasms, Intestinal Obstruction, Pancreatic Neoplasms, Adenomatous Polyposis Coli, Anastomotic Leak

NCT00927485 2020-12-16

Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)

44 enrolled 7 charts

Adenomatous Polyposis Coli

NCT00033371 2020-09-29

Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

205 enrolled 16 charts

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT04552405 2020-09-17

FAPPER

35 enrolled

Adenomatous Polyposis Coli

NCT04454151 2020-07-01

FAP

Phase 4 Unknown

Adenomatous Polyposis Coli

NCT04296851 2020-03-05

Niclosamide for Familial Adenomatous Polyposis

Phase 2 Unknown

72 enrolled

Phase EARLY_PHASE1 Terminated

Adenomatous Polyposis Coli

NCT02374931 2019-10-03

18F-FES PET/CT in Imaging Patients With Desmoid Tumors

3 enrolled

GastrointestinalSarcoma

Adenomatous Polyposis Coli, Desmoid Tumors

NCT00140894 2019-09-20

A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP) (0966-205)(TERMINATED)

Phase 4 Terminated

62 enrolled

Cancer Pain, Osteoarthritis, Adenomatous Polyposis Coli

NCT03847532 2019-04-04

MAP

25 enrolled

Adenomatous Polyposis Coli

NCT00685568 2018-11-07

Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis

GastrointestinalOther neoplasm

22 enrolled

Colonic Neoplasms, Adenomatous Polyposis Coli, Precancerous Conditions, Rectal Neoplasms, Colorectal Neoplasms

NCT00663819 2018-04-17

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

Phase NA Terminated

258 enrolled 10 charts

Colitis, Ulcerative, Diverticulitis, Adenomatous Polyposis Coli, Rectal Neoplasms

NCT01656746 2017-12-06

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Colonic Neoplasms, Crohn Disease, Peutz-Jeghers Syndrome, Adenomatous Polyposis Coli, Adenomatous Polyps

NCT00641147 2017-09-29

Curcumin in Treating Patients With Familial Adenomatous Polyposis

44 enrolled 23 charts

Adenomatous Polyposis Coli

NCT03061591 2017-02-23

Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis.

Phase 2 Unknown

40 enrolled

Adenomatous Polyposis Coli

NCT01187901 2016-06-17

FAPEST

92 enrolled 11 charts

Adenomatous Polyposis Coli

NCT00770991 2016-02-15

Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP)

34 enrolled 9 charts

Adenomatous Polyposis Coli, Polyps

NCT01245816 2015-04-24

A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)

Phase 3 Withdrawn