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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Sarcoma 4Wilms Tumor 3Rhabdoid Tumor 3Hepatoblastoma 3Carcinoma, Hepatocellular 3Stomach Neoplasms 2Rhabdomyosarcoma 2Retinoblastoma 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms, Germ Cell and Embryonal 2Melanoma 2Medulloblastoma 2Central Nervous System Neoplasms 2Carcinoma, Renal Cell 2Sarcoma, Ewing 1Sarcoma, Clear Cell 1Rectal Neoplasms 1Pancreatic Neoplasms 1Optic Nerve Glioma 1Neurofibrosarcoma 1Neuroblastoma 1Neoplasms 1Liver Neoplasms 1Kidney Neoplasms 1Gallbladder Neoplasms 1Fibrolamellar hepatocellular carcinoma 1Familial ependymoma 1Esophageal Neoplasms 1Desmoplastic Small Round Cell Tumor 1

Interventions

Thiotepa 2Filgrastim 2Cytoreduction Surgical Procedures 2Cisplatin 2spartalizumab 1sodium thiosulfate 1pembrolizumab 1fludarabine phosphate 1fludarabine 1X-Rays 1Topotecan 1Specimen Handling 1Platinum 1Peripheral Blood Stem Cell Transplantation 1Nivolumab 1Mesna 1Melphalan 1Magnetic Resonance Spectroscopy 1Ipilimumab 1Imatinib Mesylate 1Hyperthermic Intraperitoneal Chemotherapy 1HhAntag691 1Granulocyte Colony-Stimulating Factor 1Doxorubicin 1Cyclophosphamide 1Carboplatin 1Busulfan 1Bone Marrow Transplantation 1Arsenic Trioxide 1Amifostine 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Desmoplastic Small Round Cell Tumor × Mesna × Gastrointestinal × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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