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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 8Thoracic 2Other solid neoplasm 2Plasma cell 1Gastrointestinal 1

Conditions

Colorectal Neoplasms 5948Pancreatic Neoplasms 3563Carcinoma, Hepatocellular 3273Stomach Neoplasms 3057Colonic Neoplasms 2328Rectal Neoplasms 2192Esophageal Neoplasms 1801Liver Neoplasms 1247Neoplasms 1181Breast Neoplasms 1064Neoplasm Metastasis 871Carcinoma, Non-Small-Cell Lung 794Lung Neoplasms 745Cholangiocarcinoma 743Gastrointestinal Neoplasms 662Ovarian Neoplasms 630Esophageal Squamous Cell Carcinoma 585Prostatic Neoplasms 485Melanoma 457Biliary Tract Neoplasms 441Head and Neck Neoplasms 376Uterine Cervical Neoplasms 344Carcinoma, Renal Cell 329Gastrointestinal Stromal Tumors 326Adenocarcinoma Of Esophagus 315Sarcoma 304Barrett Esophagus 300Anus Neoplasms 284Gallbladder Neoplasms 283Endometrial Neoplasms 281

Interventions

HhAntag691 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Hemangioendothelioma, Epithelioid × Gastrointestinal × Clear all
NCT01154452 2018-08-15

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

National Cancer Institute (NCI)

Phase 1/2 Completed
78 enrolled 11 charts
GastrointestinalSarcoma

Malignant mesenchymal tumor, Chondrosarcoma, Extraskeletal Myxoid, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Neuroectodermal Tumors, Primitive, Peripheral, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Gastrointestinal Stromal Tumors, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

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