Announcements Trials
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Phase

Phase 1 1

Status

Completed 26Unknown 6Terminated 5Recruiting 3Active not recruiting 2Withdrawn 1Suspended 1Not yet recruiting 1Available 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 2Thoracic 1Plasma cell 1Other solid neoplasm 1Other hematologic neoplasm 1Myeloid 1Gynecologic 1Gastrointestinal 1Endocrine 1

Conditions

Colorectal Neoplasms 28Pancreatic Neoplasms 17Stomach Neoplasms 13Carcinoma, Hepatocellular 13Breast Neoplasms 9Rectal Neoplasms 7Neoplasms 7Esophageal Neoplasms 7Colonic Neoplasms 7Prostatic Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Ovarian Neoplasms 3Neoplasm Metastasis 3Lung Neoplasms 3Endometrial Neoplasms 3Diabetes Mellitus 3Crohn Disease 3Cholangiocarcinoma 3Carcinoma, Renal Cell 3Bile Duct Neoplasms 3Uterine Cervical Neoplasms 2Triple Negative Breast Neoplasms 2Sarcoma 2Peritoneal Neoplasms 2Multiple Sclerosis 2Multiple Myeloma 2Melanoma 2Liver Neoplasms 2Irritable Bowel Syndrome 2Head and Neck Neoplasms 2

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Interleukin-2 1IL32 protein, human 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Hodgkin Disease × Gastrointestinal × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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