Clinical Trials

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05546372 2026-05-26

RACCOON

122 enrolled

Klatskin Tumor

NCT05874934 2026-05-26

CHORDA-II-p

40 enrolled

Phase 2 Active not recruiting

Klatskin Tumor

NCT05564403 2026-05-13

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

66 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07030140 2026-05-01

Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma

Phase 2 Recruiting

38 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06125769 2026-04-03

LITALHICA

50 enrolled

Phase 3 Active not recruiting

Klatskin Tumor

NCT06109779 2026-03-04

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

757 enrolled

Phase 2 Active not recruiting

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06178588 2026-02-24

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

15 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05430698 2026-02-09

PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma

Phase 2 Recruiting

62 enrolled

Klatskin Tumor

NCT06739252 2026-01-28

Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA

Phase 2 Terminated

1 enrolled

Phase NA Not yet recruiting

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma, Klatskin Tumor

NCT07326189 2026-01-16

PHAE-PHCC

33 enrolled

Phase NA Not yet recruiting

Klatskin Tumor

NCT03104569 2025-12-26

Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma

100 enrolled

Cholangitis, Klatskin Tumor

NCT06420349 2025-12-22

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Phase 1 Terminated

7 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05024513 2025-12-18

Biliary Drainage Plus HAIC in Locally Advanced pCCA

127 enrolled

Klatskin Tumor

NCT06850753 2025-08-21

SURE-LT

15 enrolled

Klatskin Tumor

NCT04993131 2025-07-31

TESLA II

15 enrolled

Bile Duct Neoplasms, Klatskin Tumor

NCT03377179 2025-07-23

A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma

65 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT06493734 2025-07-15

STRONG II

30 enrolled

Klatskin Tumor

NCT06964425 2025-07-02

Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study

20 enrolled

Disease, Cholangiocarcinoma, Klatskin Tumor

NCT05239169 2025-05-01

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

40 enrolled

Phase 2/3 Not yet recruiting

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06923475 2025-04-11

NEODISCO

150 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05551299 2025-03-27

CARP

Phase 4 Recruiting

258 enrolled

Phase 2 Active not recruiting

Bile Duct Neoplasms, Klatskin Tumor

NCT06717464 2024-12-05

Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract Cancer

110 enrolled

Gallbladder Neoplasms, Klatskin Tumor

NCT05563870 2024-03-26

COMBO-RFA

30 enrolled

Klatskin Tumor

NCT01825603 2023-12-28

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Phase 1 Completed

17 enrolled

Phase NA Not yet recruiting

Gallbladder Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06175845 2023-12-19

ACTICCA-2

130 enrolled

Bile Duct Neoplasms, Bites and Stings, Cholangitis, Liver Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06106750 2023-10-30

Endoscopic Scissors Cutting Nasobiliary Duct VS Bilateral Plastic Stent

122 enrolled

Bile Duct Diseases, Gallbladder Diseases, Klatskin Tumor

NCT05681949 2023-08-24

ADBoard

1,200 enrolled

Fibrolamellar hepatocellular carcinoma, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Cholangiocarcinoma, Klatskin Tumor

NCT03003065 2023-08-22

PDT

10 enrolled

Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT04211168 2023-03-29

Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers

Phase 2 Unknown

44 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT03353181 2022-08-25

ENBD

Phase NA Withdrawn

Klatskin Tumor

NCT04611100 2022-03-23

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

70 enrolled

Klatskin Tumor

NCT02232932 2021-11-03

TRANSPHIL

60 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT04779788 2021-07-14

I-125 Seeds Loaded Stent Insertion for Inoperable Hilar Cholangiocarcinoma

100 enrolled

Klatskin Tumor

NCT03620292 2021-04-28

COUGAR

Phase 1/2 Unknown

12 enrolled

Klatskin Tumor

NCT03307538 2021-01-26

STRONG

6 enrolled

Klatskin Tumor

NCT03383796 2020-10-08

Comparing Three Dimension Laparoscopic Versus Open Surgery for Perihiliar Cholangiocarcinoma

30 enrolled

Klatskin Tumor

NCT04386772 2020-06-17

Portal Vein Embolization Using Coils Plus TAGM vs Multiple Coils for Patients With Perihilar Cholangiocarcinoma or Hepatocellular Carcinoma

56 enrolled

Carcinoma, Hepatocellular, Hypertrophy, Klatskin Tumor

NCT02082522 2019-08-28

Efficacy and Safety Study of PDT Using Photofrin in Unresectable Advanced Perihilar Cholangiocarcinoma (OPUS)

Phase 3 Terminated

28 enrolled 24 charts

Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT02108145 2019-08-01

Percutaneous Bilateral Versus Unilateral Metal Stent for Hilar Cholangiocarcinoma

Phase 2/3 Unknown

70 enrolled

Jaundice, Cholangiocarcinoma, Klatskin Tumor

NCT02955771 2019-07-17

Efficacy and Safety Study of PDT Using Deuteporfin for Unresectable Advanced Perihilar Cholangiocarcinoma

Phase 2 Terminated

7 enrolled

Klatskin Tumor

NCT03104582 2019-07-11

Best Biliary Drainage Option in Advanced Klatskin Tumor

180 enrolled

Cholangitis, Klatskin Tumor

NCT02958059 2019-01-16

Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient

400 enrolled

Cholangitis, Infections, Klatskin Tumor

NCT03527875 2018-06-06

Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice

564 enrolled

Klatskin Tumor, Jaundice, Obstructive

NCT02801500 2017-09-21

CTREG

70 enrolled

Choledochal Cyst, Klatskin Tumor, Gallstones

NCT02042443 2017-09-12

S1310

53 enrolled 13 charts

Bile Duct Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Cholangiocarcinoma, Klatskin Tumor

NCT02856568 2017-05-30

Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma

Phase 1 Withdrawn

Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT02166970 2017-03-01

Single Versus Multiple Deployment of Metallic Stents for Inoperable Malignant Hilar Biliary Obstruction

130 enrolled

Klatskin Tumor

NCT02504957 2015-10-26

Photodynamic Therapy With Polyhematoporphyrin for Malignant Biliary Obstruction

88 enrolled

Klatskin Tumor

NCT00630890 2015-09-11

Cyberknife Radiosurgery Boost for Hilar Cholangiocarcinoma (Klatskin Tumor)

Phase 1 Terminated

11 enrolled