Announcements Trials
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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 2Gastrointestinal 1Breast 1

Conditions

Esophageal Neoplasms 48Rectal Neoplasms 42Pancreatic Neoplasms 29Esophageal Squamous Cell Carcinoma 20Adenocarcinoma Of Esophagus 15Stomach Neoplasms 14Colorectal Neoplasms 8Anus Neoplasms 8Carcinoma, Hepatocellular 7Neoplasms 6Neoplasm Metastasis 6Cholangiocarcinoma 5Locally Advanced Rectal Cancer 4Uterine Cervical Neoplasms 3Sarcoma 3Melanoma 3Anal Canal Carcinoma 3Adenocarcinoma 3Vulvar Neoplasms 2Vaginal Neoplasms 2Prostatic Neoplasms 2Ovarian Neoplasms 2Gastrointestinal Neoplasms 2Gallbladder Neoplasms 2Esophageal Diseases 2Endometrial Neoplasms 2Diabetes Mellitus, Insulin-Dependent, 12 2Colonic Neoplasms 2Clinical Stage I Gastric Cancer AJCC v8 2Carcinoma, Non-Small-Cell Lung 2

Interventions

tipifarnib 1adavosertib 1Trastuzumab 1Radiotherapy 1Radiation 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Meningeal Carcinomatosis × Radiation × Gastrointestinal × Clear all
NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

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