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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 8Breast 2Gastrointestinal 1

Conditions

Rectal Neoplasms 139Esophageal Neoplasms 125Pancreatic Neoplasms 96Esophageal Squamous Cell Carcinoma 84Colorectal Neoplasms 66Adenocarcinoma Of Esophagus 53Stomach Neoplasms 40Carcinoma, Hepatocellular 40Colonic Neoplasms 19Anus Neoplasms 18Neoplasms 14Liver Neoplasms 12Cholangiocarcinoma 10Adenocarcinoma 8Carcinoma, Squamous Cell 7Bile Duct Neoplasms 7Anal Canal Carcinoma 7Head and Neck Neoplasms 6Breast Neoplasms 6Brain Neoplasms 6Prostatic Neoplasms 5Neoplasm Metastasis 5Melanoma 5Lung Neoplasms 5Gastrointestinal Neoplasms 5Gallbladder Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Uterine Cervical Neoplasms 4Sarcoma 4Vulvar Neoplasms 3

Interventions

tipifarnib 1adavosertib 1Trastuzumab 1Radiotherapy 1Radiation 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Meningeal Carcinomatosis × Radiotherapy × Gastrointestinal × Clear all
NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

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