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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gastrointestinal 1

Conditions

Carcinoma, Hepatocellular 46Colorectal Neoplasms 33Stomach Neoplasms 31Esophageal Squamous Cell Carcinoma 27Esophageal Neoplasms 14Rectal Neoplasms 12Cholangiocarcinoma 11Colonic Neoplasms 9Pancreatic Neoplasms 7Neoplasm Metastasis 6Sarcoma 5Carcinoma, Non-Small-Cell Lung 5Locally Advanced Rectal Cancer 4Biliary Tract Neoplasms 4Triple Negative Breast Neoplasms 3Small Cell Lung Carcinoma 3Recurrence 3Melanoma 3Liver Neoplasms 3Carcinoma, Renal Cell 3Carcinoma 3Adenocarcinoma Of Esophagus 3Uterine Cervical Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Neoplasms 2Mesothelioma 2Lung Neoplasms 2HER2-positive Gastric Cancer 2Endometrial Neoplasms 2Digestive System Neoplasms 2

Interventions

tislelizumab 1Cetuximab 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Metastatic Solid Tumors × tislelizumab × Gastrointestinal × Clear all
NCT06585488 2026-06-03

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

BeOne Medicines

Phase 1 Terminated
47 enrolled
GastrointestinalOther solid neoplasmThoracic

Metastatic Solid Tumors

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