Clinical Trials

EndocrineGastrointestinalHead & NeckNETSarcomaThoracic

500 enrolled 2 FDA

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT06051695 2026-05-26

EVEREST-2

GastrointestinalGynecologicOther solid neoplasmThoracic

474 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT00342654 2026-05-22

Nutrition Intervention Trials in Linxian Follow-up Study

Completed

32,902 enrolled

Phase 1 Active not recruiting

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT05277051 2026-05-22

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

152 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05577143 2026-05-22

BACCHUS

303 enrolled

Colonic Neoplasms, Neoplasms

NCT07023289 2026-05-22

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Phase 2 Recruiting

140 enrolled

Neoplasms, Colorectal Neoplasms

NCT07377487 2026-05-22

INDIGO

EndocrineGastrointestinalNET

51 enrolled

Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Colorectal Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT07578571 2026-05-22

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

BreastGastrointestinalThoracic

175 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07602504 2026-05-22

China Metastatic Liver Cancer Clinical Registry Cohort Database

2,000 enrolled

Liver Diseases, Liver Neoplasms, Neoplasms, Colorectal Neoplasms

NCT06768164 2026-05-20

BYQoL-GC

Phase 3 Recruiting

250 enrolled

Neoplasms, Stomach Neoplasms

NCT06989437 2026-05-20

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Phase 2/3 Recruiting

982 enrolled

Anorexia, Cachexia, Fatigue, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT07205731 2026-05-20

SAFE ESO

Phase 2 Recruiting

95 enrolled

Esophageal Squamous Cell Carcinoma, Neoplasms

NCT04901702 2026-05-19

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

CNSGastrointestinalGenitourinarySarcoma

90 enrolled

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT05468359 2026-05-19

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

64 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma, Hepatocellular, Neoplasms

NCT04984733 2026-05-18

ELEVATE

Phase 2 Completed

13 enrolled

Esophageal Neoplasms, Neoplasms

NCT07094204 2026-05-18

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Phase 1 Active not recruiting

364 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT05462717 2026-05-15

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

222 enrolled

GastrointestinalGynecologicThoracic

Appendiceal Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Pancreatic Ductal

NCT06043947 2026-05-15

SURVIMON

Active not recruiting

100,000 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms

NCT07224464 2026-05-15

The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

BreastGastrointestinalGynecologicThoracic

12 enrolled

Hyperthermia, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Cholangiocarcinoma

NCT04486378 2026-05-14

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

Phase 2 Active not recruiting

327 enrolled

Neoplasms, Colorectal Neoplasms

NCT05715255 2026-05-14

Adaptive Symptom Self-Management Immunotherapy Study

BreastDermatologicGastrointestinalThoracic

400 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Rectal Neoplasms, Skin Neoplasms

NCT07086833 2026-05-14

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

40 enrolled

Colonic Diseases, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Colorectal Neoplasms

NCT06119217 2026-05-13

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

Phase 2 Completed

194 enrolled 16 charts

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT06938971 2026-05-13

REACH

150 enrolled

Motor Activity, Neoplasms, Colorectal Neoplasms

NCT07244835 2026-05-13

A Study of DEG6498 in Participants With Solid Tumors

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

100 enrolled

Glioblastoma, Carcinoma, Hepatocellular, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Neurofibrosarcoma

NCT07578337 2026-05-13

NUMANTIA-2

Phase 2 Not yet recruiting

40 enrolled

Neoplasms, Pancreatic Neoplasms

NCT05919264 2026-05-12

FOG-001 in Locally Advanced or Metastatic Solid Tumors

CNSGastrointestinalGenitourinaryGynecologicSarcoma

595 enrolled

Craniopharyngioma, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT05645510 2026-05-11

LONGEVITI

BreastDermatologicGastrointestinalGenitourinaryGynecologicPlasma cellThoracic

75 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05647122 2026-05-11

EGRET

GastrointestinalHead & NeckThoracic

403 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Neoplasms, Colorectal Neoplasms

NCT05655494 2026-05-08

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

BreastDermatologicGastrointestinalGenitourinaryThoracic

350 enrolled

Breast Neoplasms, Colonic Neoplasms, Fibrocystic Breast Disease, Gastrointestinal Diseases, Lung Neoplasms, Neoplasms, Prostatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT05786482 2026-05-08

EMPOwer

Phase NA Completed

825 enrolled

Anxiety Disorders, Depression, Digestive System Diseases, Heart Failure, Liver Cirrhosis, Liver Cirrhosis, Biliary, Neoplasms, Renal Insufficiency, Chronic

NCT05954312 2026-05-08

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

290 enrolled

Adenocarcinoma Of Esophagus, Neoplasms

NCT06380816 2026-05-08

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

BreastGastrointestinalGynecologicHead & NeckThoracic

167 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT06828588 2026-05-08

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

Phase EARLY_PHASE1 Recruiting

30 enrolled

BreastGastrointestinal

Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT07529808 2026-05-08

ChefHat-001

Phase 1/2 Not yet recruiting

164 enrolled

Adenocarcinoma, Colonic Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT07000253 2026-05-07

OMEC-5

Phase 2/3 Recruiting

290 enrolled

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT06835569 2026-05-06

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

188 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07387263 2026-05-06

Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing

BreastGastrointestinalGenitourinaryGynecologic

180 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT05914987 2026-05-05

PREDICT-PANC

1,000 enrolled

BreastGastrointestinalGenitourinaryThoracic

Neoplasms, Pancreatic Neoplasms

NCT07354919 2026-05-05

AxeCan

Phase 2 Recruiting

34 enrolled

Breast Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT07567716 2026-05-05

Infiltration Pattern of Locally Advanced ESCC

Enrolling by invitation

30 enrolled

Phase 3 Active not recruiting

Margins of Excision, Esophageal Squamous Cell Carcinoma, Neoplasms

NCT03504397 2026-05-04

Spotlight

565 enrolled 63 charts 1 FDA

Phase 1 Enrolling by invitation

Adenocarcinoma, Neoplasms, Stomach Neoplasms

NCT07218003 2026-05-04

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

149 enrolled

BreastGastrointestinalGenitourinaryGynecologicThoracic

Esophageal Squamous Cell Carcinoma, Adenocarcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT00001823 2026-05-01

Evaluation for NCI Surgery Branch Clinical Research Protocols

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT00068003 2026-05-01

Harvesting Cells for Experimental Cancer Treatments

Enrolling by invitation

7,000 enrolled

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms

NCT02838836 2026-05-01

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

620 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Neoplastic Cells, Circulating, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04084067 2026-04-30

Indocyanine Green (ICG) Guided Tumor Resection

CNSGastrointestinalGenitourinaryLymphoidSarcoma

230 enrolled

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lymphoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT04981119 2026-04-30

BASECAMP-1

BreastGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

200 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT05297734 2026-04-30

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer