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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 2Head & Neck 2Gynecologic 2Genitourinary 2CNS 2Thoracic 1Other solid neoplasm 1Lymphoid 1Gastrointestinal 1Endocrine 1Dermatologic 1

Conditions

Colorectal Neoplasms 142Stomach Neoplasms 104Carcinoma, Non-Small-Cell Lung 87Pancreatic Neoplasms 81Carcinoma, Hepatocellular 74Melanoma 59Esophageal Neoplasms 57Ovarian Neoplasms 50Squamous Cell Carcinoma of Head and Neck 49Parkinson Disease 4, Autosomal Dominant Lewy Body 44Neoplasms 43Carcinoma, Renal Cell 43Triple Negative Breast Neoplasms 39Neoplasm Metastasis 37Lung Neoplasms 36Breast Neoplasms 36Uterine Cervical Neoplasms 35Cholangiocarcinoma 35Esophageal Squamous Cell Carcinoma 33Head and Neck Neoplasms 29Endometrial Neoplasms 29Biliary Tract Neoplasms 26Carcinoma, Transitional Cell 25Urinary Bladder Neoplasms 23Colonic Neoplasms 23Small Cell Lung Carcinoma 20Prostatic Neoplasms 17Liver Neoplasms 17Adenocarcinoma Of Esophagus 15Adenocarcinoma 15

Interventions

Cyclophosphamide 3fludarabine 2Vorinostat 2Sirolimus 2Mesna 2Melphalan 2Granulocyte Colony-Stimulating Factor 2Busulfan 2sodium thiosulfate 1ripretinib 1repotrectinib 1pralsetinib 1pembrolizumab 1pegylated granulocyte colony-stimulating factor 1lutetium Lu 177 dotatate 1fludarabine phosphate 1etoposide phosphate 1copper dotatate CU-64 1Ursodeoxycholic Acid 1Topotecan 1Thrombopoietin 1Thiotepa 1Therapeutics 1Sunitinib 1Stem Cell Transplantation 1Simvastatin 1Radiotherapy, Image-Guided 1Radiation 1Psychiatric Rehabilitation 1Plicamycin 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × pembrolizumab × Gastrointestinal × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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